Document Detail

Reproducibility of thallium-201 exercise SPECT studies.
MedLine Citation:
PMID:  8046474     Owner:  NLM     Status:  MEDLINE    
A detailed analysis of intrapatient reproducibility of exercise SPECT thallium studies is presented. METHODS: Twenty patients in stable condition were re-examined with exercise-redistribution SPECT201 Tl within 3-9 days without intervening procedures. At peak stress, 3.5 mCi 201Tl were given intravenously 1 min prior to exercise termination. SPECT imaging started at 5 and 180 min. Acquisition and processing protocols were the same for all studies. Coronary angiography was performed on 19 patients and showed coronary artery disease (CAD) in 18, and no CAD in one; one patient did not have coronary arteriography. RESULTS: For 16 of 20 patients, exercise levels and ECG were comparable for both studies. Ten patients reproduced ST-segment depression; two reproduced angina; one had left bundle branch block (LBBB) on both studies after 1 min of exercise. The remaining seven patients had no ECG changes or symptoms during exercise. Four of 20 (20%) thallium scans differed: three in degree of redistribution and one (5%) in presence of a second stress defect. In three of four patients whose thallium studies showed some nonreproducibility, there were differences in exercise. Thallium results were identical in 15 of 16 patients whose ECG/exercise tests were reproducible (94%). Interobserver agreement was 95%. CONCLUSION: There was excellent reproducibility of 201Tl SPECT scintigraphy in patients who reproduced exercise test performance and symptoms.
N P Alazraki; E G Krawczynska; E G DePuey; J A Ziffer; J P Vansant; R I Pettigrew; A Taylor; S B King; E V Garcia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  35     ISSN:  0161-5505     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1994-08-30     Completed Date:  1994-08-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1237-44     Citation Subset:  IM    
Department of Radiology, Emory University School of Medicine, Atlanta, Georgia.
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MeSH Terms
Coronary Angiography
Coronary Disease / epidemiology,  radionuclide imaging*
Exercise Test
Heart / radionuclide imaging*
Middle Aged
Observer Variation
Reproducibility of Results
Thallium Radioisotopes / diagnostic use*
Time Factors
Tomography, Emission-Computed, Single-Photon / statistics & numerical data*
Reg. No./Substance:
0/Thallium Radioisotopes

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