Document Detail

Reproducibility of noninvasive cardiac output during arm exercise in spinal cord injury.
MedLine Citation:
PMID:  18247251     Owner:  NLM     Status:  MEDLINE    
The carbon dioxide (CO(2)) rebreathing method is a noninvasive technique to estimate cardiac output during exercise, but few data are available on the validity and reliability of this measure in individuals with spinal cord injury (SCI). Sixteen male subjects with SCI (mean age 45 +/- 9, seven paraplegic and nine tetraplegic) underwent three submaximal steady state arm ergometer exercise tests. We estimated cardiac output using the exponential CO(2) rebreathing technique at an individualized exercise intensity approximating 50% of peak oxygen uptake. Mean values for the cardiac output measurements were 13.0 +/- 2.4, 13.3 +/- 2.0, and 13.4 +/- 1.7 L/min; the difference among the trials was not significant (p = 0.54). The typical error was 1.80 +/- 0.85 L/min, the limits of agreement were 11.3 to 15.3 L/min, the coefficient of variation was 5.4% +/- 3.4%, and the intraclass correlation coefficient was 0.85 (95% confidence interval = 0.70-0.94). The test-to-test variation in estimated cardiac output during arm ergometry in individuals with SCI is similar to that observed in studies that used this technique in ambulatory persons. The 5% relative variation between tests suggests that the CO(2) rebreathing technique for estimating cardiac output can be performed in SCI individuals with acceptable reproducibility.
Jonathan Myers; Heather Brown; Susan Smith; Inder Perkash; B Jenny Kiratli
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Journal of rehabilitation research and development     Volume:  44     ISSN:  1938-1352     ISO Abbreviation:  J Rehabil Res Dev     Publication Date:  2007  
Date Detail:
Created Date:  2008-02-05     Completed Date:  2009-05-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8410047     Medline TA:  J Rehabil Res Dev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  547-52     Citation Subset:  IM    
Cardiology Division, Department of Veterans Affairs (VA) Palo Alto Health Care System, Palo Alto, CA 94304, USA.
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MeSH Terms
Arm / physiology*
Cardiac Output / physiology*
Cervical Vertebrae
Exercise Test / methods*
Middle Aged
Oxygen Consumption / physiology
Paraplegia / diagnosis*,  etiology,  physiopathology
Quadriplegia / diagnosis*,  etiology,  physiopathology
Reproducibility of Results
Spinal Cord Injuries / complications,  diagnosis*,  physiopathology

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