Document Detail

Reproducibility of the motor unit number index (MUNIX) in normal controls and amyotrophic lateral sclerosis patients.
MedLine Citation:
PMID:  20976784     Owner:  NLM     Status:  MEDLINE    
The motor unit number index (MUNIX) refers to an electrophysiologic technique that measures the approximate number of motor units using the surface electromyographic interference pattern (SIP) recorded during voluntary contraction. This study was done to assess the reproducibility of MUNIX performed on hypothenar muscles in 62 normal controls and 22 amyotrophic lateral sclerosis (ALS) patients. Inter- and intraoperator correlation coefficients for MUNIX were 0.74 and 0.86, respectively, in normal controls, and 0.95 and 0.93, respectively, in ALS patients (P < 0.01 in all). Inter- and intraoperator coefficients of variation for MUNIX measurements were 17.5% and 15.3%, respectively, in normal controls, and 23.7% and 24.0%, respectively, in ALS patients. This study shows a good correlation for MUNIX between intra- and interoperator results in both normal controls and ALS patients. The test-retest variability seems to be greater in ALS patients compared with normal controls, but this will need to be confirmed in future studies. Sources of variability should be identified and corrected for clinical use.
Suk-Won Ahn; Su-Hyun Kim; Jee-Eun Kim; Sung-Min Kim; Seung Hyun Kim; Kyung Seok Park; Jung-Joon Sung; Kwang-Woo Lee; Yoon-Ho Hong
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Muscle & nerve     Volume:  42     ISSN:  1097-4598     ISO Abbreviation:  Muscle Nerve     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-26     Completed Date:  2010-11-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  United States    
Other Details:
Languages:  eng     Pagination:  808-13     Citation Subset:  IM    
Department of Neurology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Republic of Korea.
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MeSH Terms
Action Potentials / physiology
Aging / physiology
Amyotrophic Lateral Sclerosis / pathology*
Analysis of Variance
Middle Aged
Motor Neurons / pathology*
Muscle Fibers, Skeletal / pathology*
Muscle, Skeletal / innervation*,  pathology*
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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