Document Detail

Reproducibility of diagnostic results by a multivariate computer ECG analysis program (AVA 3.5).
MedLine Citation:
PMID:  338306     Owner:  NLM     Status:  MEDLINE    
Reproducibility of the AVA program (version 3.5) was tested (1) by analyzing the same analog tracing 10 times in 150 patients, and (2) by studying the influence of 12 different sets of prior probabilities (PRP), using the digital data from a total of 2718 patients. The same QRS-T diagnosis plus or minus 8 percentage points was found in patients with high posterior probabilities. Variability for the P wave diagnosis was twice as high as for QRS-T results. Failure to select the appropriate set of PrP markedly influenced reproducibility. This was especially true for right ventricular hypertrophy and pulmonary emphysema. 'Mispriorizing' in a subgroup of 199 patients with well-documented myocardial infarction lowered the total number of correct ECG diagnoses on the average between 4.8 and 35%. These results are inherent to Bayes' theorem where PrP are used to achieve minimum assignment error in populations, but where Prp errors may result in wide classification discrepancies. Without errors in PrP reproducibility by the VA program was found to be very high.
J L Willems; J Pardaens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cardiology     Volume:  6     ISSN:  0301-4711     ISO Abbreviation:  Eur J Cardiol     Publication Date:    1977 Oct-Nov
Date Detail:
Created Date:  1978-02-18     Completed Date:  1978-02-18     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404054     Medline TA:  Eur J Cardiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  229-43     Citation Subset:  IM    
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MeSH Terms
Analysis of Variance
Diagnosis, Computer-Assisted*
Heart Diseases / diagnosis*
Myocardial Infarction / diagnosis
Statistics as Topic

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