Document Detail

Reproducibility of Optical Coherence Tomography Measurements in Children.
MedLine Citation:
PMID:  22967864     Owner:  NLM     Status:  Publisher    
PURPOSE: To determine the interobserver and intraobserver reproducibility of a Fourier-domain optical coherence tomography device (Cirrus HD OCT; Carl Zeiss Meditec, Dublin, California, USA) in normal pediatric eyes. DESIGN: Prospective cross-sectional study. METHODS: One hundred healthy children were recruited prospectively and consecutively. Only 1 randomly chosen eye per subject was included in the study. The eye underwent 3 scans centered on the optic disc and another 3 scans centered on the macula that were acquired by a single operator. A fourth examination was performed by a second operator. Interobserver and intraobserver reproducibility were described by intraclass correlation coefficients (ICCs) and coefficients of variation (COVs). RESULTS: The mean age was 9.15 years (range, 6.22 to 11.31 years; standard deviation, 1.05 years). Mean retinal nerve fiber layer thickness was 99.53 μm (standard deviation, 10.10 μm), and mean macular thickness was 282.91 μm (standard deviation, 11.83 μm). All the parameters evaluated were highly reproducible. Intraobserver COVs of the retinal nerve fiber layer measurements ranged from 2.24% to 5.52%, and the COV of macular thickness was 0.97%. The intraclass correlation coefficient was greater than 0.8 for all the parameters. The interobserver COV ranged from 2.23% to 5.18%, and the COV of macular thickness was 0.82%. In all the evaluated parameters, the intraclass correlation coefficient was more than 0.75. Repeatability was slightly better in children older than 10 years than in children younger than 9 years. CONCLUSIONS: Retinal nerve fiber layer and macular measurements obtained by Fourier-domain optical coherence tomography showed good repeatability for healthy eyes in the pediatric population. Cirrus HD OCT examinations of the retina are reliable in children.
Irene Altemir; Victoria Pueyo; Noemi Elía; Vicente Polo; Jose M Larrosa; Daniel Oros
Related Documents :
10911374 - Evaluation of human herpesvirus type 8 infection in childhood langerhans cell histiocyt...
15454834 - Viral infections in juvenile myelomonocytic leukemia: prevalence and clinical implicati...
20705544 - Impact of a citywide sanitation program in northeast brazil on intestinal parasites inf...
14533674 - Random spatial distribution of schistosoma mansoni and hookworm infections among school...
21796574 - Incidence of previously unknown cardiac malformations in asymptomatic children after pr...
2357094 - Decline in head growth and cognitive impairment in survivors of acute lymphoblastic leu...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-8
Journal Detail:
Title:  American journal of ophthalmology     Volume:  -     ISSN:  1879-1891     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Ophthalmology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Minocycline Controls Clinical Outcomes and Inflammatory Cytokines in Moderate and Severe Meibomian G...
Next Document:  Clinical Outcomes of Phototherapeutic Keratectomy in Eyes With Thiel-Behnke Corneal Dystrophy.