Document Detail

Reproducibility of MRI measurements of right ventricular size and function in patients with normal and dilated ventricles.
MedLine Citation:
PMID:  18581357     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine the inter- and intraobserver reproducibility of cardiac magnetic resonance (CMR)-derived measurements of right ventricular (RV) mass, volume, and function in patients with normal and dilated ventricles.
MATERIALS AND METHODS: CMR studies of 60 patients in three groups were studied: a normal RV group (N = 20) and two groups with RV dilation-atrial septal defect (ASD) (N = 20) and repaired tetralogy of Fallot (TOF) (N = 20). Two independent observers analyzed each study on two separate occasions. Inter- and intraobserver reproducibility of biventricular mass, volume, ejection fraction (EF), and stroke volume (SV) measurements were calculated.
RESULTS: High intraclass correlation coefficients (ICC) were found for interobserver (ICC = 0.94-0.99) and intraobserver (ICC = 0.96-0.99) comparisons of RV and left ventricular (LV) mass, volume, and SV measurements. RV and LV EF measurements were less reproducible (ICC = 0.79-0.87). RV mass measurements were significantly less correlated than the respective LV measurements. Small but statistically significant differences in correlation were noted in RV measurements across groups.
CONCLUSION: Except for RV mass, inter- and intraobserver reproducibility of RV size and function measurements is high and generally comparable to that in the LV in patients with both normal and dilated RV.
Christiaan F Mooij; Cornelis J de Wit; Dionne A Graham; Andrew J Powell; Tal Geva
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  28     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-07-10     Completed Date:  2008-11-04     Revised Date:  2014-09-09    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  67-73     Citation Subset:  IM    
Copyright Information:
(c) 2008 Wiley-Liss, Inc.
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MeSH Terms
Dilatation, Pathologic
Heart Septal Defects, Atrial / pathology*
Heart Ventricles / anatomy & histology*,  pathology*
Magnetic Resonance Imaging*
Observer Variation
Organ Size
Reproducibility of Results
Tetralogy of Fallot / pathology*
Ventricular Function, Right / physiology*
Grant Support
1P50 HL 074734-01/HL/NHLBI NIH HHS; P50 HL074734/HL/NHLBI NIH HHS; P50 HL074734-01/HL/NHLBI NIH HHS

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