Document Detail


Representation of the ipsilateral visual field by neurons in the macaque lateral intraparietal cortex depends on the forebrain commissures.
MedLine Citation:
PMID:  20660427     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our eyes are constantly moving, allowing us to attend to different visual objects in the environment. With each eye movement, a given object activates an entirely new set of visual neurons, yet we perceive a stable scene. One neural mechanism that may contribute to visual stability is remapping. Neurons in several brain regions respond to visual stimuli presented outside the receptive field when an eye movement brings the stimulated location into the receptive field. The stored representation of a visual stimulus is remapped, or updated, in conjunction with the saccade. Remapping depends on neurons being able to receive visual information from outside the classic receptive field. In previous studies, we asked whether remapping across hemifields depends on the forebrain commissures. We found that, when the forebrain commissures are transected, behavior dependent on accurate spatial updating is initially impaired but recovers over time. Moreover, neurons in lateral intraparietal cortex (LIP) continue to remap information across hemifields in the absence of the forebrain commissures. One possible explanation for the preserved across-hemifield remapping in split-brain animals is that neurons in a single hemisphere could represent visual information from both visual fields. In the present study, we measured receptive fields of LIP neurons in split-brain monkeys and compared them with receptive fields in intact monkeys. We found a small number of neurons with bilateral receptive fields in the intact monkeys. In contrast, we found no such neurons in the split-brain animals. We conclude that bilateral representations in area LIP following forebrain commissures transection cannot account for remapping across hemifields.
Authors:
Catherine A Dunn; Carol L Colby
Related Documents :
11039697 - Computational model of dot-pattern selective cells.
2288897 - Binocular neurons in the nucleus of the basal optic root (nbor) of the pigeon are selec...
16307237 - Postcentral neurons with covert receptive fields in conscious macaque monkeys: their se...
4005527 - Visual field recovery from scotoma in patients with postgeniculate damage. a review of ...
9928307 - Mechanisms of spontaneous activity in the developing spinal cord and their relevance to...
2475947 - Pharmacological analysis of cortical circuitry.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.     Date:  2010-07-21
Journal Detail:
Title:  Journal of neurophysiology     Volume:  104     ISSN:  1522-1598     ISO Abbreviation:  J. Neurophysiol.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-03     Completed Date:  2011-02-11     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0375404     Medline TA:  J Neurophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2624-33     Citation Subset:  IM    
Affiliation:
Department of Neuroscience and Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Corpus Callosum / physiology*
Electrophysiology
Eye Movements / physiology
Macaca mulatta
Neurons / physiology*
Parietal Lobe / physiology*
Photic Stimulation
Prosencephalon / physiology*
Split-Brain Procedure
Visual Fields / physiology*
Grant Support
ID/Acronym/Agency:
EY-08908/EY/NEI NIH HHS; EY-12032/EY/NEI NIH HHS; MH-45156/MH/NIMH NIH HHS; P41-RR-03631/RR/NCRR NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Kainate receptor-induced ectopic spiking of CA3 pyramidal neurons initiates network bursts in neonat...
Next Document:  How global are olfactory bulb oscillations?