Document Detail

Reporting of funding sources and conflict of interest in the supportive and palliative oncology literature.
MedLine Citation:
PMID:  22771126     Owner:  NLM     Status:  MEDLINE    
CONTEXT: The reporting of funding support and conflict of interest has not been examined in the supportive/palliative oncology literature.
OBJECTIVES: We examined the frequency of funding and conflict of interest reporting and various study characteristics associated with such reporting.
METHODS: We systematically searched MEDLINE PubMed, PsycInfo, EMBASE, ISI Web of Science, and CINAHL for original studies related to palliative care and cancer in the first six months of 2004 and 2009. For each article, we reviewed the study design, research topic, journal type, and reporting of funding and conflict of interest.
RESULTS: Three hundred forty-four (41%) and 504 (59%) of 848 articles were from 2004 and 2009, respectively. Five hundred two of 848 (59%) studies reported no funding sources, whereas 216 (26%), 70 (8%), 34 (4%), and 26 (3%) reported one, two, three, and four or more sources, respectively. Key funding sources included governmental agencies (n=182/848, 21%), philanthropic foundations (n=163/848, 19%), university departments (n=76/848, 9%), and industry (n=27/848, 3%). Conflict of interest was not reported in 436 of 848 (51%) studies, and only 94 of 848 (11%) explicitly stated no conflict of interest. Other than extramural funding, conflict of interest reporting of any kind was extremely rare (mostly less than 1%). Conflict of interest reporting increased between 2004 and 2009 (39% vs. 55%, P<0.001). Both funding and conflict of interest reporting were associated with prospective studies, larger sample sizes, nontherapeutic studies, North American authors, and publication in palliative care/oncology journals (P≤0.008 for all comparisons).
CONCLUSION: A majority of supportive/palliative oncology studies did not report funding sources and conflict of interest, raising the need for standardization.
David Hui; Akhila Reddy; Henrique A Parsons; Eduardo Bruera
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2012-07-07
Journal Detail:
Title:  Journal of pain and symptom management     Volume:  44     ISSN:  1873-6513     ISO Abbreviation:  J Pain Symptom Manage     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-03     Completed Date:  2013-01-21     Revised Date:  2014-01-31    
Medline Journal Info:
Nlm Unique ID:  8605836     Medline TA:  J Pain Symptom Manage     Country:  United States    
Other Details:
Languages:  eng     Pagination:  421-30     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.
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MeSH Terms
Conflict of Interest*
Medical Oncology / ethics*
Palliative Care / ethics*
Publishing / standards*
Research Design
Research Support as Topic / ethics*
Grant Support
R01 CA122292/CA/NCI NIH HHS; R01 CA124481/CA/NCI NIH HHS; R01 NR010162/NR/NINR NIH HHS; R01CA122292-01/CA/NCI NIH HHS; R01CA124481-01/CA/NCI NIH HHS; R01NR010162-01A1/NR/NINR NIH HHS

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