Document Detail


Reported respiratory symptom intensity in asthmatics during exposure to aerosolized Florida red tide toxins.
MedLine Citation:
PMID:  17885863     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Florida red tides are naturally occurring blooms of the marine dinoflagellate, Karenia brevis. K. brevis produces natural toxins called brevetoxins. Brevetoxins become part of the marine aerosol as the fragile, unarmored cells are broken up by wave action. Inhalation of the aerosolized toxin results in upper and lower airway irritation. Symptoms of brevetoxin inhalation include: eye, nose, and throat irritation, coughing, wheezing, chest tightness, and shortness of breath. Asthmatics appear to be more sensitive to the effects of inhaled brevetoxin. This study examined data from 97 asthmatics exposed at the beach for 1 hour during K. brevis blooms, and on separate occasions when no bloom was present. In conjunction with extensive environmental monitoring, participants were evaluated utilizing questionnaires and pulmonary function testing before and after a 1-hour beach walk. A modified Likert scale was incorporated into the questionnaire to create respiratory symptom intensity scores for each individual pre- and post-beach walk. Exposure to Florida red tide significantly increased the reported intensity of respiratory symptoms; no significant changes were seen during an unexposed period. This is the first study to examine the intensity of reported respiratory symptoms in asthmatics after a 1-hour exposure to Florida red tide.
Authors:
Alexyz Milian; Kate Nierenberg; Lora E Fleming; Judy A Bean; Adam Wanner; Andrew Reich; Lorraine C Backer; David Jayroe; Barbara Kirkpatrick
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The Journal of asthma : official journal of the Association for the Care of Asthma     Volume:  44     ISSN:  0277-0903     ISO Abbreviation:  J Asthma     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-09-21     Completed Date:  2007-12-14     Revised Date:  2014-03-19    
Medline Journal Info:
Nlm Unique ID:  8106454     Medline TA:  J Asthma     Country:  United States    
Other Details:
Languages:  eng     Pagination:  583-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Air Pollutants / adverse effects*
Air Pollution / adverse effects*
Animals
Asthma / etiology*
Child
Dinoflagellida
Environmental Monitoring
Epidemiological Monitoring
Female
Florida / epidemiology
Humans
Inhalation Exposure / adverse effects
Male
Marine Toxins / adverse effects*
Middle Aged
Severity of Illness Index
Grant Support
ID/Acronym/Agency:
P01 ES 10594/ES/NIEHS NIH HHS; P01 ES010594/ES/NIEHS NIH HHS; P01 ES010594-07/ES/NIEHS NIH HHS
Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Gymnodinium breve toxin; 0/Marine Toxins
Comments/Corrections

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