Document Detail

Report on a multicenter fMRI quality assurance protocol.
MedLine Citation:
PMID:  16649196     Owner:  NLM     Status:  MEDLINE    
Temporal stability during an fMRI acquisition is very important because the blood oxygen level-dependent (BOLD) effects of interest are only a few percent in magnitude. Also, studies involving the collection of groups of subjects over time require stable scanner performance over days, weeks, months, and even years. We describe a protocol designed by one of the authors that has been tested for several years within the context of a large, multicenter collaborative fMRI research project (FIRST-BIRN). A full description of the phantom, the quality assurance (QA) protocol, and the several calculations used to measure performance is provided. The results obtained with this protocol at multiple sites over time are presented. These data can be used as benchmarks for other centers involved in fMRI research. Some issues with the various protocol measures are highlighted and discussed, and possible protocol improvements are also suggested. Overall, we expect that other fMRI centers will find this approach to QA useful and this report may facilitate developing a similar QA protocol locally. Based on the findings reported herein, the authors are convinced that monitoring QA in this way will improve the quality of fMRI data.
Lee Friedman; Gary H Glover
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Journal of magnetic resonance imaging : JMRI     Volume:  23     ISSN:  1053-1807     ISO Abbreviation:  J Magn Reson Imaging     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-23     Completed Date:  2006-10-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9105850     Medline TA:  J Magn Reson Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  827-39     Citation Subset:  IM    
Copyright Information:
Copyright 2006 Wiley-Liss, Inc.
Department of Psychiatry, University of California-Irvine, Irvine, California, USA.
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MeSH Terms
Brain Mapping / instrumentation,  methods*
Calibration / standards
Image Enhancement / methods
Image Interpretation, Computer-Assisted / methods*
Magnetic Resonance Imaging / instrumentation,  methods*,  standards*
Multicenter Studies as Topic*
Phantoms, Imaging / standards
Quality Assurance, Health Care / methods*,  standards*
Reproducibility of Results
Sensitivity and Specificity
United States
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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