| Report of a metaplastic carcinoma of the breast with multi-directional differentiation: an adenoid cystic carcinoma, a spindle cell carcinoma and melanoma. | |
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MedLine Citation:
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PMID: 18283489 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Metaplastic carcinoma of the breast is a heterogeneous neoplasia, generally composed of both epithelial and mesenchymal components. We report an unusual case of mammary metaplastic carcinoma in a 51-year-old female patient. Needle core biopsy from the tumour mass showed malignant epithelial and sarcomatous features. The resection specimen revealed a multi-directional tumour differentiation consisting predominantly of: firstly, a poorly differentiated basaloid epithelial cell type, consistent with an adenoid cystic carcinoma; secondly, areas of a spindle cell carcinoma; and, thirdly, areas with a melanocytic differentiation. This is the first report on a metaplastic carcinoma of the breast presenting as an admixture of an adenoid cystic carcinoma and melanoma. |
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Authors:
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Aurelia Noske; Michael Schwabe; Stefan Pahl; Eva Fallenberg; Christiane Richter-Ehrenstein; Manfred Dietel; Glen Kristiansen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Virchows Archiv : an international journal of pathology Volume: 452 ISSN: 0945-6317 ISO Abbreviation: Virchows Arch. Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-07-21 Completed Date: 2008-07-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9423843 Medline TA: Virchows Arch Country: Germany |
Other Details:
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Languages: eng Pagination: 575-9 Citation Subset: IM |
Affiliation:
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Institute of Pathology, Charité University Hospital Berlin, Campus Mitte, Charitéplatz 1, Berlin 10117, Germany. aurelia.noske@charite.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy, Fine-Needle Breast Neoplasms / diagnosis, pathology* Carcinoma / diagnosis, pathology* Carcinoma, Adenoid Cystic / diagnosis, pathology* Cell Transformation, Neoplastic / pathology* Female Humans Melanoma / diagnosis, pathology* Metaplasia / diagnosis, pathology Middle Aged |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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