Document Detail


Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring.
MedLine Citation:
PMID:  14770088     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The field of tumor angiogenesis has seen explosive growth over the last 5 years. Preclinical as well as early clinical evaluation of novel compounds is progressing at a rapid pace. To gain a perspective on the field and to take stock of advances in the understanding of molecular mechanisms underlying the process of tumor angiogenesis as well as ways of monitoring the activity of agents, the Society for Biologic Therapy and the National Cancer Institute's Vascular Biology Faculty convened a Workshop on Angiogenesis Monitoring in November 2002. The Workshop was composed of invited speakers and participants from academia, industry, and government. It was divided into 3 sessions, each chaired by leaders in the field. The first focused on advances in the understanding of the cellular and molecular mechanisms of angiogenesis in tumors. The second examined preclinical assay systems that are useful in vascular biology. The third addressed the translation to the clinic and monitoring of antiangiogenic activity of agents in patients and novel trial designs. What follows is a summary of the discussions and findings of each session.
Authors:
Donald M McDonald; Beverly A Teicher; William Stetler-Stevenson; Sylvia S W Ng; William D Figg; Judah Folkman; Douglas Hanahan; Robert Auerbach; Michael O'Reilly; Roy Herbst; David Cheresh; Michael Gordon; Alexander Eggermont; Steven K Libutti
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Publication Detail:
Type:  Congresses    
Journal Detail:
Title:  Journal of immunotherapy (Hagerstown, Md. : 1997)     Volume:  27     ISSN:  1524-9557     ISO Abbreviation:  J. Immunother.     Publication Date:    2004 Mar-Apr
Date Detail:
Created Date:  2004-02-10     Completed Date:  2004-11-22     Revised Date:  2008-03-18    
Medline Journal Info:
Nlm Unique ID:  9706083     Medline TA:  J Immunother     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161-75     Citation Subset:  IM    
Affiliation:
University of California at San Francisco, San Francisco, CA, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Clinical Trials as Topic
Endothelium / cytology
Humans
Immunotherapy / methods*
Models, Biological
Neoplasms / blood supply*,  therapy*
Neovascularization, Pathologic*
Tumor Markers, Biological
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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