Document Detail

Report of a case of Streptococcus agalactiae mycotic aneurysm and review of the literature.
MedLine Citation:
PMID:  18573788     Owner:  NLM     Status:  MEDLINE    
A unique case of mycotic aneurysm of the abdominal aorta caused by Streptococcus agalactiae in an afebrile patient presenting with abdominal pain is described. Although this bacterium is associated with a variety of infections in human beings, aortitis is uncommon. Chronic alcoholism and diabetes mellitus are the 2 major predisposing conditions for group B Streptococci infection and both were present in this case. The abdominal pain and elevated inflammatory markers in the absence of fever were elusive in presentation; however, the diagnosis of mycotic aneurysm was established by abdominal computed tomography scan. The patient was treated successfully by resection of the diseased aorta and aortic allograft replacement. Culture of the excised tissue grew Streptococcus agalactiae sensitive to penicillin G and (other commonly tested antibiotics) fluoroquinolones. A prolonged course of moxifloxacin (for 6 months) was administered due to the persistence of elevated inflammatory markers and was remarkably well tolerated. Sixteen months after stopping the antibiotics, the patient is doing well, and the control imaging studies are satisfactory.
Kavitha Chandrikakumari; Jean Baptiste Giot; Laurence de Leval; Etienne Creemers; Philippe Leonard; Didier Mukeba; Michel Moutschen; Frederic Frippiat
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of surgical pathology     Volume:  16     ISSN:  1066-8969     ISO Abbreviation:  Int. J. Surg. Pathol.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-24     Completed Date:  2008-10-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9314927     Medline TA:  Int J Surg Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  314-9     Citation Subset:  IM    
Department of Infectious Diseases, Center Hospitalier Universitaire de Ligeg, Ligeg, Belgium.
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MeSH Terms
Aneurysm, Infected / diagnosis*,  microbiology,  therapy
Anti-Infective Agents / therapeutic use
Aorta, Abdominal / microbiology,  pathology,  surgery
Aortic Aneurysm, Abdominal / microbiology,  pathology*,  therapy
Aza Compounds / therapeutic use
Quinolines / therapeutic use
Streptococcal Infections / complications,  pathology*,  therapy
Streptococcus agalactiae / isolation & purification*
Tomography, X-Ray Computed
Treatment Outcome
Reg. No./Substance:
0/Anti-Infective Agents; 0/Aza Compounds; 0/Quinolines; 0/moxifloxacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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