Document Detail

Report of the Subcommittee on Control of Anticoagulation on the determination of the anticoagulant effects of apixaban: communication from the SSC of the ISTH.
MedLine Citation:
PMID:  24597497     Owner:  NLM     Status:  Publisher    
The oral direct factor Xa inhibitor apixaban is approved for prevention of ischemic stroke in patients with atrial fibrillation (1) and for prophylaxis of postoperative venous thromboembolism following elective knee or hip replacement surgery (2). Studies have shown efficacy and safety for patients with acute deep vein thrombosis compared to vitamin-K antagonists (3), and for prolonged prophylaxis of recurrent events compared to placebo (4). Therapy with apixaban is given at fixed daily doses without laboratory guided adjustment. No study has proved the benefit of dose adjustment on clinical outcome (5). This article is protected by copyright. All rights reserved.
Job Harenberg; Shanshan Du; Christel Weiss; Roland Krämer; Debra Hoppensteadt; Jeanine Walenga;
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-5
Journal Detail:
Title:  Journal of thrombosis and haemostasis : JTH     Volume:  -     ISSN:  1538-7836     ISO Abbreviation:  J. Thromb. Haemost.     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-3-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101170508     Medline TA:  J Thromb Haemost     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
This article is protected by copyright. All rights reserved.
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