Document Detail


Repolarization analysis in children with the long QT syndrome.
MedLine Citation:
PMID:  14716636     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
QT duration changes were analysed in 26 children with long QT syndrome (median age 9 years). With 12-lead Holter recordings, we found that macroscopically QT adaptation to heart rate changes was slow and only 3 of 26 patients showed abrupt changes in QT interval duration. These changes in the time domain were always accompanied by changes of STT morphology in the 3 of 26 patients. Application of Bazett's heart rate correction algorithm was inappropriate to show true QT changes in this young patient group due to temporary typical large cycle length variations, where moreover an overcorrection of the heart rate impact resulted in reflection of RR interval changes rather than true QT duration changes.
Authors:
Konrad Brockmeier; Markus Khalil; Narayanswami Sreeram; Herbert E Ulmer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  36 Suppl     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  2003  
Date Detail:
Created Date:  2004-01-12     Completed Date:  2004-04-27     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  209-12     Citation Subset:  IM    
Affiliation:
Pediatric Cardiology, University of Cologne, Köln, Germany. k.brockmeier@uni-koeln.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
Electrocardiography*
Electrocardiography, Ambulatory
Female
Heart Rate
Humans
Infant
Long QT Syndrome / physiopathology*
Male

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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