Document Detail


Replication of the R6K plasmid during the Escherichia coli cell cycle.
MedLine Citation:
PMID:  1732198     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The cell-cycle replication pattern of the R6K plasmid has been investigated by using the membrane-elution technique to produce cells labelled at different times during the division cycle and scintillation counting for quantitative analysis of radioactive plasmid DNA. The high-copy plasmid R6K replicates exponentially in a cell-cycle-independent manner. A mini-R6K plasmid deleted for the ori alpha origin of replication also replicates, exponentially in a cell-cycle-independent manner.
Authors:
J D Keasling; B O Palsson; S Cooper
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of bacteriology     Volume:  174     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-02-27     Completed Date:  1992-02-27     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1060-2     Citation Subset:  IM    
Affiliation:
Department of Chemical Engineering, University of Michigan, Ann Arbor 48109-2136.
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MeSH Terms
Descriptor/Qualifier:
Cell Cycle / physiology*
DNA Replication*
Escherichia coli / physiology*
Plasmids / physiology*
Grant Support
ID/Acronym/Agency:
R01 GM44022-01A1/GM/NIGMS NIH HHS
Comments/Corrections

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