| Replacing short-acting nifedipine with alternative medications at a large health maintenance organization. | |
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MedLine Citation:
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PMID: 9607386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In response to recent evidence about the safety of calcium channel blockers, Group Health Cooperative of Puget Sound (GHC), a large health maintenance organization, implemented a plan in April 1996 to reevaluate the medications of 1349 patients who were taking short-acting nifedipine. Following the intervention, 79.8% of patients taking short-acting nifedipine discontinued use, and 45.6% switched to once-daily felodipine. By presenting physicians and patients with recent evidence about the safety of short-acting nifedipine, a large health maintenance organization was able to motivate broad-scale changes to safer alternative drug therapies. |
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Authors:
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R C Kaplan; B M Psaty; D Kriesel; S R Heckbert; N L Smith; C Gillett; A G Golston |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of hypertension Volume: 11 ISSN: 0895-7061 ISO Abbreviation: Am. J. Hypertens. Publication Date: 1998 Apr |
Date Detail:
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Created Date: 1998-07-27 Completed Date: 1998-07-27 Revised Date: 2009-02-24 |
Medline Journal Info:
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Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 471-7 Citation Subset: IM |
Affiliation:
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Cardiovascular Health Research Unit, Department of Epidemiology, University of Washington, Seattle 98101, USA. rkaplan@u.washington.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Calcium Channel Blockers / adverse effects*, therapeutic use Cohort Studies Delayed-Action Preparations Drug Utilization / trends Felodipine / administration & dosage, therapeutic use* Female Follow-Up Studies Health Maintenance Organizations* Humans Hypertension / drug therapy* Male Nifedipine / adverse effects*, therapeutic use Retreatment Safety |
| Grant Support | |
ID/Acronym/Agency:
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AG09556/AG/NIA NIH HHS; HL40628/HL/NHLBI NIH HHS; HL43201/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Calcium Channel Blockers; 0/Delayed-Action Preparations; 21829-25-4/Nifedipine; 72509-76-3/Felodipine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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