Document Detail


Reperfusion therapy in out-of-hospital cardiac arrest: current insights.
MedLine Citation:
PMID:  17239516     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although early care in out-of-hospital cardiac arrest has been improved over the past decades, survival remains poor and neurological performance after survival is often impaired. Consequently, new therapies are needed to improve outcome. As thrombotic processes such as acute myocardial infarction or pulmonary embolism are frequent causes of cardiac arrest, therapies like fibrinolysis or percutaneous coronary intervention are of interest. Both therapies can restore coronary and pulmonary perfusion in cardiac arrest patients and, additionally, fibrinolysis might prevent microthrombi to the brain. In this review, the rationale, safety and efficacy of reperfusion therapy in patients with out-of-hospital cardiac arrest will be discussed.
Authors:
Wessel Keuper; Hendrik-Jan Dieker; Marc A Brouwer; Freek W A Verheugt
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Publication Detail:
Type:  Journal Article; Review     Date:  2007-01-18
Journal Detail:
Title:  Resuscitation     Volume:  73     ISSN:  0300-9572     ISO Abbreviation:  Resuscitation     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-20     Completed Date:  2007-11-13     Revised Date:  2009-08-25    
Medline Journal Info:
Nlm Unique ID:  0332173     Medline TA:  Resuscitation     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  189-201     Citation Subset:  IM    
Affiliation:
Radboud University Nijmegen Medical Centre, Department of Cardiology, Geert Grooteplein 10, 6525 GA Nijmegen, The Netherlands. w.keuper@cardio.umcn.nl <w.keuper@cardio.umcn.nl>
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MeSH Terms
Descriptor/Qualifier:
Cardiopulmonary Resuscitation*
Emergency Medical Services*
Fibrinolytic Agents / pharmacology*
Heart Arrest / therapy*
Humans
Treatment Outcome
Chemical
Reg. No./Substance:
0/Fibrinolytic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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