| Reperfusion of low attenuation areas complicating subarachnoid hemorrhage. | |
| | |
MedLine Citation:
|
PMID: 16671432 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Hypoattenuation areas shown on brain CT scans after subarachnoid hemorrhage (SAH) are believed to be associated with persistent ischemia. The aim of this study was to evaluate regional cerebral blood flow (rCBF) in hypoattenuation areas and its evolution over time by means of Xenon CT (Xe-CT). We enrolled 16 patients with SAH who developed a hypoattenuation area in the middle cerebral artery territory. Patients were studied at time zero (the first Xe-CT), within 24 to 96 hours, and 96 hours after the initial Xe-CT. We analyzed 19 hypoattenuation areas caused by vascular distortion, vasospasm, or post-surgical embolization in 48 Xe-CT studies. Areas of hypoattenuation were divided in 2 groups according to initial rCBF. In the first group (n = 15), rCBF was initially above 6 mL/100 gr/min but only 2 were still ischemic (rCBF < 18 mL/ 100 gr/min) 96 hours after the first Xe-CT, while 7 (58%) were hyperemic. Conversely, in the second group with severe ischemia (rCBF < 6 mL/100 gr/min; n = 4) mean rCBF increased (p = 0.08) but still remained below the ischemic threshold. In severely ischemic lesions, rCBF reperfusion occurs but is probably marginally relevant. Conversely, in lesions not initially severely ischemic, residual CBF gradually improved and frequently became hyperemic. The functional recovery of these zones remains to be evaluated. |
| | |
Authors:
|
F Tagliaferri; C Compagnone; E Fainardi; A Tanfani; R Pascarella; F Sarpieri; L Targa; A Chieregato |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: Acta neurochirurgica. Supplement Volume: 96 ISSN: 0065-1419 ISO Abbreviation: Acta Neurochir. Suppl. Publication Date: 2006 |
Date Detail:
|
Created Date: 2006-05-04 Completed Date: 2006-06-12 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100962752 Medline TA: Acta Neurochir Suppl Country: Austria |
Other Details:
|
Languages: eng Pagination: 85-7 Citation Subset: IM |
Affiliation:
|
Neurorianimazione, Ospedale M. Bufalini, Cesena, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Brain
/
blood supply*,
radiography* Brain Ischemia / etiology*, radiography* Cerebrovascular Circulation* Female Humans Male Middle Aged Prognosis Subarachnoid Hemorrhage / complications*, radiography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evaluation of acute perihematomal regional apparent diffusion coefficient abnormalities by diffusion...
Next Document: Stroke in the young: relationship of active cocaine use with stroke mechanism and outcome.