| Reperfusion injury after detorsion of unilateral testicular torsion. | |
| | |
MedLine Citation:
|
PMID: 8171761 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Reperfusion injury has been well documented in organs other than testis. An experimental study was conducted to investigate reperfusion injury in testes via the biochemical changes after unilateral testicular torsion and detorsion. As unilateral testicular torsion and varicocele have been shown to affect contralateral testicular blood flow, reperfusion injury was studied in both testes. Given that testicular blood flow does not return after 720 degrees testicular torsion lasting more than 3 h, the present study was conducted after 1 and 2 h of 720 degrees torsion. Adult male albino rats were divided into seven groups each containing ten rats. One group served to determine the basal values of biochemical parameters, two groups were subjected to 1 and 2 h of unilateral testicular torsion respectively, two groups were subjected to detorsion following 1 and 2 h of torsion respectively, and two groups underwent sham operations as a control. Levels of lactic acid, hypoxanthine and lipid peroxidation products were determined in testicular tissues. Values of these three parameters obtained from the sham operation control groups did not differ significantly from basal values (P > 0.05). All three parameters were increased significantly in both ipsilateral and contralateral testes after unilateral testicular torsion when compared with basal values (P < 0.01 and P < 0.05, respectively). Detorsion caused significant changes in lipid peroxidation products levels in ipsilateral but not in contralateral testes when compared with values obtained after torsion (P < 0.01 and P > 0.05, respectively). It is concluded that ipsilateral testicular torsion causes a decrease in perfusion not only in the ipsilateral but also in the contralateral testis.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
F M Akgür; K Kilinç; T Aktuğ |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Urological research Volume: 21 ISSN: 0300-5623 ISO Abbreviation: Urol. Res. Publication Date: 1993 |
Date Detail:
|
Created Date: 1994-06-01 Completed Date: 1994-06-01 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0364311 Medline TA: Urol Res Country: GERMANY |
Other Details:
|
Languages: eng Pagination: 395-9 Citation Subset: IM |
Affiliation:
|
Department of Pediatric Surgery, Dokuz Eylül University, Medical Faculty, Izmir, Turkey. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Hypoxanthine Hypoxanthines / metabolism Lactates / metabolism Lactic Acid Male Rats Reperfusion Injury / etiology, metabolism, therapy* Spermatic Cord Torsion / complications*, therapy Thiobarbituric Acid Reactive Substances / metabolism Time Factors |
| Chemical | |
Reg. No./Substance:
|
0/Hypoxanthines; 0/Lactates; 0/Thiobarbituric Acid Reactive Substances; 50-21-5/Lactic Acid; 68-94-0/Hypoxanthine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Reperfusion injury following testicular torsion and detorsion in prepubertal rats.
Next Document: Influence of urological irrigation fluids on urothelial bacterial adherence.