Document Detail

Reperfusion and compartment syndromes: strategies for prevention and treatment.
MedLine Citation:
PMID:  11400086     Owner:  NLM     Status:  MEDLINE    
Reperfusion syndrome refers to the damage done by restoration of blood flow to ischemic tissues and is distinct from the original ischemic insult itself, whereas compartment syndrome refers to the damage resulting from increased pressure within an enclosed fascial compartment that occurs after blood flow has been restored. Despite extensive experimental work directed toward the treatment of established reperfusion injury and prevention of compartment syndrome, clinical outcome over the past decade has not appreciably changed. Although the systemic insult, thought to be an inevitable result of reperfusion injury, may be less injurious than "conventional wisdom" would suggest, no better strategy for treating compartment syndrome other than early recognition and decompression has yet been developed.
S P Lyden; C K Shortell; K A Illig
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in vascular surgery     Volume:  14     ISSN:  0895-7967     ISO Abbreviation:  Semin Vasc Surg     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-06-11     Completed Date:  2001-08-09     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8809602     Medline TA:  Semin Vasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  107-13     Citation Subset:  IM    
Copyright Information:
Copyright 2001 by W.B. Saunders Company
Division of Vascular Surgery, University of Rochester Medical Center, Rochester, NY 14642, USA.
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MeSH Terms
Compartment Syndromes* / prevention & control,  therapy
Reperfusion Injury* / prevention & control,  therapy

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