Document Detail

Repeating through the insula: evidence from two consecutive strokes.
MedLine Citation:
PMID:  17762714     Owner:  NLM     Status:  MEDLINE    
Mixed transcortical aphasia is a very rare syndrome characterized by intact repetition, despite severe impairment in all other language modalities. In some cases, however, preservation of repetition is accompanied by intact reading. We report the case of a left-handed man who, after a subcortical stroke in the left hemisphere, showed the typical features of mixed transcortical aphasia with spared repetition and reading. After 10 days, a second stroke, involving the anterior insula and adjacent white matter bundles, markedly deteriorated repetition while his reading abilities recovered. By comparing features of repetition and reading before and after the second stroke, we provide evidence for the existence of a modular organization of language abilities, pointing to the primary role of the insula and surrounding white matter in phonological processing.
Antonio Carota; Jean-Marie Annoni; Paola Marangolo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuroreport     Volume:  18     ISSN:  0959-4965     ISO Abbreviation:  Neuroreport     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-31     Completed Date:  2007-10-19     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9100935     Medline TA:  Neuroreport     Country:  England    
Other Details:
Languages:  eng     Pagination:  1367-70     Citation Subset:  IM    
Department of Neurology, University Hospital of Lausanne (CHUV), CH-1011 Lausanne, Switzerland.
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MeSH Terms
Aphasia / etiology*
Brain / pathology*
Magnetic Resonance Imaging / methods
Neuropsychological Tests
Stroke / complications*,  pathology*

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