Document Detail

Repeated sperm injection under the zona following initial fertilization failure.
MedLine Citation:
PMID:  8473469     Owner:  NLM     Status:  MEDLINE    
When fertilization fails following micromanipulative under-zona insemination, it is possible to repeat the procedure adding more spermatozoa to achieve fertilization, embryonic development and pregnancy. We report on 18 human in-vitro fertilization cycles where this approach was used. In nine cycles only late-fertilized embryos were available for transfer, and these gave rise to two viable pregnancies (22.2% per transfer). In six cycles, where a mixture of late- and timely fertilized embryos were available for transfer, two viable pregnancies arose (33.3% per transfer). In three cycles no fertilization was achieved even after reinsemination by repeated under-zona insemination.
S R Wiker; M J Tucker; G Wright; H E Malter; H I Kort; J B Massey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  8     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-05-20     Completed Date:  1993-05-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  467-9     Citation Subset:  IM    
Reproductive Biology Associates, Atlanta, GA 30342.
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MeSH Terms
Embryo Transfer
Fertilization in Vitro / methods*
Spermatozoa / physiology*
Zona Pellucida*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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