| Repeated exposures to hyperbaric air suppress neurite outgrowth in PC12 cells. | |
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MedLine Citation:
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PMID: 17971265 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hyperbaric exposure induces lesions of the CNS in scuba divers. Repeated exposures to hyperbaric air at 0.5 MPa for 30 min with short intervals suppressed NGF-stimulated neurite outgrowth, concomitant with a decrease in the protein expression of ERK in PC12 cells. Hyperbaric exposure most likely causes direct lesions of neural cells. |
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Authors:
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Tetsuro Isada; Munetaka Hirose; Eri Murata; Yoko Okayama; Mayumi Takatori; Mayumi Tani; Keita Fukazawa; Masashi Hirata; Satoshi Taniguchi; Kenji Shigemi; Yoshifumi Tanaka |
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Publication Detail:
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Type: Journal Article Date: 2007-11-01 |
Journal Detail:
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Title: The journal of physiological sciences : JPS Volume: 57 ISSN: 1880-6546 ISO Abbreviation: J Physiol Sci Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-11-26 Completed Date: 2008-08-12 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 101262417 Medline TA: J Physiol Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 321-5 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology and Reanimatology, Faculty of Medical Sciences, Fukui University, Eiheijicho, Yoshidagun, Fukui, 910-1193, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Air Pressure* Animals Cell Differentiation / physiology* Extracellular Signal-Regulated MAP Kinases / analysis, metabolism Nerve Growth Factor / pharmacology Neurites / drug effects, physiology* PC12 Cells Phosphorylation Rats Receptor, trkA / metabolism |
| Chemical | |
Reg. No./Substance:
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9061-61-4/Nerve Growth Factor; EC 2.7.10.1/Receptor, trkA; EC 2.7.11.24/Extracellular Signal-Regulated MAP Kinases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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