| Repeated breathlessness experiences induced by hypercapnia: differential effects on intensity and unpleasantness. | |
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MedLine Citation:
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PMID: 19201712 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The present study investigated the effect of repeated hypercapnic challenges on the sensory (intensity [I]) and affective (unpleasantness [U]) dimensions of breathlessness. METHODS: Three subsequent rebreathing trials (Read, 1968) were administered to healthy men and women (n = 39). The I and U of breathlessness were rated every 20 s during the baseline, rebreathing, and recovery phases. Breathing behavior (fractional end-tidal CO(2) [Fetco(2)] and minute ventilation [Ve]) was monitored continuously. Intraindividual linear regression slopes for Fetco(2) and Ve] were calculated and standardized, separately for both rating dimensions. RESULTS: Both the absolute magnitude and the slope of the I of breathlessness were higher compared to U (p < 0.05). Across-trial habituation of the peak I and U of breathlessness occurred in both genders (p < 0.001), but habituation was larger for the U than for the I (p = 0.05). CONCLUSIONS: The findings show that the sensory and affective dimensions of breathlessness can meaningfully be distinguished during hypercapnic challenges and that repeated exposures have different effects on both dimensions. |
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Authors:
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Li Wan; Ilse Van Diest; Steven De Peuter; Katleen Bogaerts; Omer Van den Bergh |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chest Volume: 135 ISSN: 1931-3543 ISO Abbreviation: Chest Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-09 Completed Date: 2009-04-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
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Languages: eng Pagination: 455-61 Citation Subset: AIM; IM |
Affiliation:
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Department of Psychology, University of Leuven, Leuven, Belgium. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Blood Gas Analysis Carbon Dioxide / blood* Dyspnea / etiology, physiopathology* Female Humans Hypercapnia / complications, physiopathology, psychology* Illness Behavior Inhalation / physiology Male Reference Values Risk Assessment Sampling Studies Sensitivity and Specificity Sensory Thresholds Sex Factors Young Adult |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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