| Repeated balloon inflations do not diminish ST segment elevation even though coronary collateral recruitment is promoted in pigs. | |
| | |
MedLine Citation:
|
PMID: 17299262 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: Attempts to demonstrate preconditioning during repeated angioplasty balloon inflations (BIs) have not been universally successful. The main obstacle is that the first BI is unreliable, due to the variable degrees of occlusion by the deflated balloon. In the present study, we examined whether ST segment elevation decreases and evaluated its relation to collateral recruitment during repeated angioplasty BIs in the pig. METHODS AND RESULTS: Twenty male pigs, 7 months old, under general anesthesia, underwent 3 repeated BIs of 120 s, with a 5-min interval between them, in the left anterior descending artery or the right coronary artery. A pressure wave wire was used for the measurement of coronary wedge pressure and to obtain the intracoronary ST segment elevation. Intracoronary ST segment elevation was 1.97 +/- 0.76 mV during the 1st BI, 2.09 +/- 0.82 mV during the 2nd BI and 1.84 +/- 0.82 mV during the 3rd BI (p = n.s.). Coronary wedge pressure was 12 +/- 6, 18 +/- 18 and 20 +/- 20 mm Hg (p < 0.05 vs. 1st BI) during the 3 BIs, respectively. CONCLUSION: Repeated BIs do not diminish ST segment elevation in the pig model, even though coronary collateral recruitment is promoted. |
| | |
Authors:
|
Theodore Lyras; Apostolos Papalois; Lykourgos Klamargias; Stamatis Kyrzopoulos; Paraskevi Dafnomili; Zenon S Kyriakides |
Publication Detail:
|
Type: Journal Article Date: 2007-02-13 |
Journal Detail:
|
Title: Cardiology Volume: 108 ISSN: 1421-9751 ISO Abbreviation: Cardiology Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-11-16 Completed Date: 2008-01-10 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 1266406 Medline TA: Cardiology Country: Switzerland |
Other Details:
|
Languages: eng Pagination: 340-4 Citation Subset: IM |
Copyright Information:
|
(c) 2007 S. Karger AG, Basel. |
Affiliation:
|
Second Department of Cardiology, Hellenic Red Cross Hospital, Athens, Greece. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Angioplasty, Transluminal, Percutaneous Coronary* Animals Collateral Circulation* Coronary Circulation* Disease Models, Animal Electrocardiography Ischemic Preconditioning, Myocardial / methods* Male Reoperation Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Valvular heart disease by transthoracic echocardiography is associated with focal brain injury and c...
Next Document: WITHDRAWN: Cardiac Troponin T: An Early Molecule Marker of Normalization of Left Ventricular Ejectio...