Document Detail


Repeated assessments of food security predict CD4 change in the setting of antiretroviral therapy.
MedLine Citation:
PMID:  21694604     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Food insecurity is highly prevalent in HIV-infected populations, and analyses utilizing multiple assessments of food security to predict CD4 change are lacking. Five hundred Ninety-two patients with ≥ 4 food security assessments were followed prospectively. In the final model, for patients using antiretroviral therapy, increases in CD4 counts were on average 99.5 cells less for individuals with at least 1 episode of food insecurity compared with those consistently food secure (P < 0.001). Other sociodemographic factors were not predictive. Repeated assessments of food security are potent predictors of treatment response notwithstanding antiretroviral therapy use. Potential mechanisms for this association are proposed.
Authors:
James H McMahon; Christine A Wanke; Julian H Elliott; Sally Skinner; Alice M Tang
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of acquired immune deficiency syndromes (1999)     Volume:  58     ISSN:  1944-7884     ISO Abbreviation:  J. Acquir. Immune Defic. Syndr.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-22     Completed Date:  2011-11-02     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  100892005     Medline TA:  J Acquir Immune Defic Syndr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  60-3     Citation Subset:  IM; X    
Affiliation:
Department of Infectious Diseases, Alfred Hospital, Melbourne, Australia. ja.mcmahon@alfred.org.au
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-HIV Agents / therapeutic use*
Antiretroviral Therapy, Highly Active
CD4 Lymphocyte Count*
Female
Food Supply / economics,  statistics & numerical data*
HIV Infections / drug therapy*,  economics
Humans
Linear Models
Male
Middle Aged
Multivariate Analysis
Poverty
Prospective Studies
Risk Factors
Substance Abuse, Intravenous
Grant Support
ID/Acronym/Agency:
P01 DK045734-10/DK/NIDDK NIH HHS; P01 DK45734/DK/NIDDK NIH HHS; P30 AI042853/AI/NIAID NIH HHS; P30 AI042853-14/AI/NIAID NIH HHS; P30 AI42853/AI/NIAID NIH HHS; P30 DA013868-09/DA/NIDA NIH HHS; P30DA13868/DA/NIDA NIH HHS; R01 HL 65947/HL/NHLBI NIH HHS; R01 HL065947-05/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Anti-HIV Agents
Comments/Corrections

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