| Repeated assessments of food security predict CD4 change in the setting of antiretroviral therapy. | |
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MedLine Citation:
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PMID: 21694604 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Food insecurity is highly prevalent in HIV-infected populations, and analyses utilizing multiple assessments of food security to predict CD4 change are lacking. Five hundred Ninety-two patients with ≥ 4 food security assessments were followed prospectively. In the final model, for patients using antiretroviral therapy, increases in CD4 counts were on average 99.5 cells less for individuals with at least 1 episode of food insecurity compared with those consistently food secure (P < 0.001). Other sociodemographic factors were not predictive. Repeated assessments of food security are potent predictors of treatment response notwithstanding antiretroviral therapy use. Potential mechanisms for this association are proposed. |
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Authors:
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James H McMahon; Christine A Wanke; Julian H Elliott; Sally Skinner; Alice M Tang |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of acquired immune deficiency syndromes (1999) Volume: 58 ISSN: 1944-7884 ISO Abbreviation: J. Acquir. Immune Defic. Syndr. Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-08-22 Completed Date: 2011-11-02 Revised Date: 2012-09-27 |
Medline Journal Info:
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Nlm Unique ID: 100892005 Medline TA: J Acquir Immune Defic Syndr Country: United States |
Other Details:
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Languages: eng Pagination: 60-3 Citation Subset: IM; X |
Affiliation:
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Department of Infectious Diseases, Alfred Hospital, Melbourne, Australia. ja.mcmahon@alfred.org.au |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anti-HIV Agents / therapeutic use* Antiretroviral Therapy, Highly Active CD4 Lymphocyte Count* Female Food Supply / economics, statistics & numerical data* HIV Infections / drug therapy*, economics Humans Linear Models Male Middle Aged Multivariate Analysis Poverty Prospective Studies Risk Factors Substance Abuse, Intravenous |
| Grant Support | |
ID/Acronym/Agency:
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P01 DK045734-10/DK/NIDDK NIH HHS; P01 DK45734/DK/NIDDK NIH HHS; P30 AI042853-14/AI/NIAID NIH HHS; P30 AI42853/AI/NIAID NIH HHS; P30 DA013868-09/DA/NIDA NIH HHS; P30DA13868/DA/NIDA NIH HHS; R01 HL 65947/HL/NHLBI NIH HHS; R01 HL065947-05/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Anti-HIV Agents |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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