Document Detail

Repeated arterial thrombosis as a complication of carboplatin-based chemotherapy.
MedLine Citation:
PMID:  16849025     Owner:  NLM     Status:  MEDLINE    
We describe a case of a 57-year-old woman with repeated acute arterial thrombosis of the femoral arteries following intravenous carboplatin-based combination chemotherapy for metastatic ovarian carcinoma. By extensive workup, no other known causes of arterial thrombosis were found. To our knowledge, this is the first case describing arterial thrombosis occurring as a complication of carboplatin therapy.
Kakkhee K Yeung; Erwin Coster; A W Floris Vos; Roger K Van der Vijgh; Mattheus A M Linsen; Willem Wisselink
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Vascular     Volume:  14     ISSN:  1708-5381     ISO Abbreviation:  Vascular     Publication Date:    2006 Jan-Feb
Date Detail:
Created Date:  2006-07-19     Completed Date:  2006-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101196722     Medline TA:  Vascular     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  51-4     Citation Subset:  IM    
Department of Vascular Surgery, VU University Medical Center, Amsterdam, the Netherlands.
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MeSH Terms
Acute Disease
Antineoplastic Agents / adverse effects*
Antineoplastic Combined Chemotherapy Protocols / adverse effects
Carboplatin / adverse effects*
Femoral Artery* / radiography
Middle Aged
Ovarian Neoplasms / drug therapy
Thrombosis / chemically induced*,  radiography
Reg. No./Substance:
0/Antineoplastic Agents; 41575-94-4/Carboplatin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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