Document Detail

Repeated "all out" interval exercise causes an increase in serum hepcidin concentration in both trained and untrained men.
MedLine Citation:
PMID:  23850671     Owner:  NLM     Status:  Publisher    
This investigation assessed effects of high-intensity interval exercise (HIE; triple Wingate anaerobic test) on inflammatory markers, iron metabolism and hepcidin concentrations. Group of highly trained judo athletes (TR) and non-trained control males (CG) completed a triple Wingate test separated by 4.5min rest. Venous blood samples were collected before, immediately after, 1h, 24h, and 5days following exercise and analysed for serum of IL-6, IL-10, iron, and ferritin. Physiological response to exercise was also determined. Concentration of IL-6 and hepcidin increased 1h after exercise in both groups (p<0.05). Hepcidin returned post testing 24h in TR, whereas in CG it remained elevated during 5days following exercise. Changes in hepcidin did not correlate with shifts in serum IL-6, iron and ferritin concentrations. Gathered data suggest that following HIE, hepcidin increased independently of IL-6 and neither blood nor storage iron affected this phenomena.
Jędrzej Antosiewicz; Jan J Kaczor; Katarzyna Kasprowicz; Radosław Laskowski; Sylwester Kujach; Marcin Luszczyk; Lukasz Radziminski; Ewa Ziemann
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-6-20
Journal Detail:
Title:  Cellular immunology     Volume:  283     ISSN:  1090-2163     ISO Abbreviation:  Cell. Immunol.     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-7-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1246405     Medline TA:  Cell Immunol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  12-17     Citation Subset:  -    
Copyright Information:
Copyright © 2013 Elsevier Inc. All rights reserved.
Warsaw School of Social Sciences and Humanities, Department of Sport Psychology, Poland.
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