| Repeatability and validity of IUATLD Respiratory Questionnaire responses as a measure of asthma in an Ethiopian population. | |
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MedLine Citation:
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PMID: 19413213 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To assess the repeatability and validity of the IUATLD respiratory symptoms questionnaire in relation to exercise-induced bronchoconstriction or bronchodilator responses in a community in southern Ethiopia. DESIGN: A case-control study. SETTING: Rural and small town setting in southern Ethiopia, April to May 2006. SUBJECTS: Two hundred and forty seven adults and children who previously reported wheeze in the past year, and 174 who did not. INTERVENTIONS: Administered IUATLD bronchial symptoms questionnaire; standardised free-running exercise test or (for those with airflow obstruction) assessment of bronchodilator response to inhaled salbutamol. RESULTS: Kappa values for four-week repeatability for the wheeze and asthma questions were 0.61 (95% CI 0.52 to 0.70) and 0.75 (0.63 to 0.87), respectively. Of the 58 people who reported wheeze in 2003 and in April 2006, only five had a positive exercise test or bronchodilator challenge (Positive Predictive Value (PPV) 0.09, 95% CI 0.01 to 0.22). Of the 12 who reported asthma in 2003 and April 2006, three had a positive result to either to exercise test or bronchodilator challenge test (PPV 0.25, 95% CI 0.05 to 0.50). CONCLUSION: Our findings suggest that self-reported wheeze and asthma have good short-term repeatability, but do not closely reflect exercise-induced bronchospasm or bronchodilator responsiveness. The validity of questionnaire methods of studying asthma epidemiology in developing countries needs further investigation. |
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Authors:
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W Denboba; A Venn; J Britton; G Davey |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Studies |
Journal Detail:
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Title: East African medical journal Volume: 85 ISSN: 0012-835X ISO Abbreviation: East Afr Med J Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2009-05-05 Completed Date: 2009-05-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372766 Medline TA: East Afr Med J Country: Kenya |
Other Details:
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Languages: eng Pagination: 582-8 Citation Subset: IM |
Affiliation:
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School of Public Health, Addis Ababa University, P.O. Box 9086, Addis Ababa, Ethiopia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Asthma / diagnosis* Bronchial Provocation Tests Case-Control Studies Cross-Sectional Studies Ethiopia Exercise Test Female Humans Male Questionnaires* Reproducibility of Results Respiratory Sounds / etiology |
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