Document Detail


Repeatability of sites of sleep-induced upper airway obstruction. A 2-night study based on recordings of airway pressure and flow.
MedLine Citation:
PMID:  11548907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To evaluate repeatability of overnight continuous airway pressure and flow recordings for assessment of obstructive sites and their distribution in patients with obstructive sleep apnea (OSA). STUDY DESIGN: Open, prospective study of 30 men with sleep-induced obstructive events (apnea and hypopnea). METHODS: Repeated ambulatory sleep recordings of airway pressure and flow to assess the localization of sites of obstructive events were compared. Obstructive sites were divided into upper (transpalatal) or lower (subpalatal). The exact distribution of obstructive sites was expressed as percentage upper obstructive events. A cut-off at apnea index (AI) = 5 was used for comparison between frequent and infrequent obstructers. RESULTS: Eighty-two percent (14/17) of patients with frequent, and 58% of those with infrequent apneic events maintained their predominant site of obstructive events classified as upper (transpalatal) or lower (subpalatal) [72% (21/29) in the entire group]. We found a significant correlation between recordings for the percentage upper apneic (R = 0.54, P = 0.024, n = 17) and hypopneic (R = 0.59, P = 0.012, n = 17) events in patients with frequent, but not in those with infrequent apneic events. Patients who had the vast majority of obstructive events located at a single site were more stable than those with more evenly distributed obstructive events. CONCLUSION: Repeatability of sites of obstructive events is influenced by the severity of illness and the degree of upper or lower obstructive predominance. The distribution of sites of obstructive events (classified as mainly "upper"/"lower" or as percent upper obstructive events of all) can be identified with relative confidence in patients who have frequent apneic events (AI > or = 5) or a high degree of upper or lower obstructive predominance and especially in those who have a combination of these two criteria.
Authors:
J Rollheim; M Tvinnereim; J Sitek; T Osnes
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery     Volume:  258     ISSN:  0937-4477     ISO Abbreviation:  Eur Arch Otorhinolaryngol     Publication Date:  2001 Jul 
Date Detail:
Created Date:  2001-09-10     Completed Date:  2002-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9002937     Medline TA:  Eur Arch Otorhinolaryngol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  259-64     Citation Subset:  IM    
Affiliation:
Colosseumklinikken, Oslo, Norway. jaroll@frisurf.no
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MeSH Terms
Descriptor/Qualifier:
Adult
Airway Obstruction / pathology*,  physiopathology*
Airway Resistance / physiology*
Catheterization
Humans
Male
Monitoring, Ambulatory
Prospective Studies
Reproducibility of Results
Respiratory System / pathology,  physiopathology
Severity of Illness Index
Sleep Apnea Syndromes / pathology*,  physiopathology*
Sleep Apnea, Obstructive / pathology*,  physiopathology*
Time Factors
Transducers, Pressure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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