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Repeatability of ocular aberration measurements in patients with keratoconus.
MedLine Citation:
PMID:  21936862     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Citation information: Jinabhai A, Radhakrishnan H & O'Donnell C. Repeatability of ocular aberration measurements in patients with keratoconus. Ophthalmic Physiol Opt 2011. doi: 10.1111/j.1475-1313.2011.00868.x ABSTRACT: Purpose:  To explore the repeatability of lower-order and higher-order ocular aberrations measured in patients with keratoconus. Methods:  The IRX-3 (Imagine Eyes, Paris, France) aberrometer was used to record lower-order and higher-order aberrations in 31 eyes of 31 patients with keratoconus. Four monocular measurements were taken consecutively for each patient. The aberrometry data were analysed up to the 5th Zernike order for a 4-mm pupil diameter. The data were evaluated using repeated-measures anova and Friedman analyses. Repeatability was analysed using within-subject standard deviation (S(W) ) and the repeatability limit (r) calculated as 1.96 ×√2 × S(w) . Results:  Of the 11 aberration terms evaluated, the repeatability of Z (2,0) (mean = 1.36 μm; S(W)  = 0.09 μm; r = 0.26 μm); Z (2,±2) RMS (mean = 1.05 μm; S(W)  = 0.09 μm; r = 0.24 μm) and Z (4,0) aberrations (mean = 0.34 μm; S(W)  = 0.09 μm; r = 0.24 μm) showed the highest variability. In contrast, Z (3,±1) RMS aberrations (mean = 0.85 μm; S(W)  = 0.06 μm; r = 0.16 μm) and Z (4,±2) RMS aberrations (mean = 0.40 μm; S(W)  = 0.07 μm; r = 0.18 μm) showed comparatively better repeatability. Conclusions:  The lower-order and higher-order aberrations measured in this group of keratoconic patients showed higher levels of variability compared to previous investigations of visually-normal subjects. These results may be of interest to eyecare practitioners involved in the design and fitting of aberration-controlling contact lenses for patients with keratoconus.
Authors:
Amit Jinabhai; Hema Radhakrishnan; Clare O'Donnell
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-21
Journal Detail:
Title:  Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)     Volume:  -     ISSN:  1475-1313     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8208839     Medline TA:  Ophthalmic Physiol Opt     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 The College of Optometrists.
Affiliation:
Faculty of Life Sciences, The University of Manchester, Manchester School of Life & Health Sciences, Aston University, Birmingham Optegra Eye Sciences, Optegra Manchester Eye Hospital, Manchester, UK.
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