Document Detail

Repeat balloon dilation of congenital valvar aortic stenosis: immediate results and midterm outcome.
MedLine Citation:
PMID:  10385159     Owner:  NLM     Status:  MEDLINE    
While balloon dilation (BD) has become the initial treatment for congenital valvar aortic stenosis (CVAS) at many institutions, repeat BD for recurrent obstruction has been reported only in a few. Between January 1985 and December 1996, 298 patients (70 neonates) underwent BD, 34 of whom underwent a repeat BD without mortality. A greater proportion of neonates had a repeat BD (26% vs. 8%, P < 0.001). At repeat BD (1 day-7.5 years post initial BD), the mean peak-to-peak gradient was reduced from 67+/-24 to 36+/-16 mm Hg (P < 0.0001). Aortic regurgitation (AR) increased immediately in 26%, being moderate or more in 24%. During a mean follow-up of 5.2 years, there was one surgically related death. Of the 33 survivors, 6 had surgery for residual stenosis and/or AR. Among the remaining 27 patients, 96% were asymptomatic, the peak instantaneous aortic valve Doppler gradient was 50+/-15 mm Hg with AR absent in 8%, mild in 62%, and moderate or more in 31%. In conclusion, repeat BD is effective and without mortality. AR was at least moderate in 24% of patients immediately after a second BD. Repeat BD was more common in patients who underwent the initial BD as neonates.
G M Satou; S B Perry; J E Lock; G E Piercey; J F Keane
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  47     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  1999 May 
Date Detail:
Created Date:  1999-07-29     Completed Date:  1999-07-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  47-51     Citation Subset:  IM    
Department of Cardiology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
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MeSH Terms
Aortic Valve Insufficiency / etiology,  radiography
Aortic Valve Stenosis / congenital,  therapy*
Balloon Dilatation*
Child, Preschool
Coronary Angiography
Infant, Newborn
Treatment Outcome

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