Document Detail

Repair of atrial septal defect with Eisenmenger syndrome after long-term sildenafil therapy.
MedLine Citation:
PMID:  20417794     Owner:  NLM     Status:  MEDLINE    
We report a woman with atrial septal defect and severe pulmonary hypertension with 25.0 Wood unit.m(2) of indexed total pulmonary vascular resistance. She underwent successful corrective repair of atrial septal defect after 2 years of treatment with sildenafil, and has been monitored for 4 years after repair. This case supports a "treat and repair" approach using advanced pulmonary vasodilator therapy in selected patients with inoperable severe pulmonary hypertension associated with atrial septal defect.
Young-Hwue Kim; Jeong Jin Yu; Tae-Jin Yun; Yonghee Lee; Yong Beom Kim; Hyung Soon Choi; Won Kyoung Jhang; Hong Ju Shin; Jeong-Jun Park; Dong-Man Seo; Jae-Kon Ko; In-Sook Park
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  89     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-06-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  1629-30     Citation Subset:  AIM; IM    
Copyright Information:
Copyright (c) 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Department of Pediatrics, College of Medicine, University of Ulsan, Seoul, Korea.
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MeSH Terms
Cardiac Surgical Procedures / methods*
Echocardiography, Doppler, Color
Eisenmenger Complex / complications,  diagnosis*,  therapy
Follow-Up Studies
Heart Catheterization / methods
Heart Septal Defects, Atrial / complications,  diagnosis*,  surgery*
Hypertension, Pulmonary / complications,  diagnosis*,  drug therapy
Long-Term Care
Piperazines / therapeutic use*
Purines / therapeutic use
Risk Assessment
Severity of Illness Index
Sulfones / therapeutic use*
Time Factors
Tomography, X-Ray Computed / methods
Treatment Outcome
Vasodilator Agents / therapeutic use
Reg. No./Substance:
0/Piperazines; 0/Purines; 0/Sulfones; 0/Vasodilator Agents; 139755-83-2/sildenafil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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