Document Detail

Reorganization of cerebral circuits in human brain lesion.
MedLine Citation:
PMID:  15986729     Owner:  NLM     Status:  MEDLINE    
Recovery after focal brain lesions is supposed to be mediated by cerebral reorganization. Stroke is a powerful model to study these processes in the human brain, since middle cerebral artery infarction is a common neurological disease with a clearly defined onset of a lateralized sensorimotor deficit syndrome. Brain tumours constitute a further model differing from stroke by their slow lesion dynamics. Evidence from functional neuroimaging and transcranial magnetic stimulation will be presented showing that recovery of hand function is related to reorganization of local perilesional and large-scale circuits involving the contralesional hemisphere.
R J Seitz; R Kleiser; C M Bütefisch
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Acta neurochirurgica. Supplement     Volume:  93     ISSN:  0065-1419     ISO Abbreviation:  Acta Neurochir. Suppl.     Publication Date:  2005  
Date Detail:
Created Date:  2005-06-30     Completed Date:  2005-07-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  100962752     Medline TA:  Acta Neurochir Suppl     Country:  Austria    
Other Details:
Languages:  eng     Pagination:  65-70     Citation Subset:  IM    
Department of Neurology, Biomedical Research Center, Heinrich-Heine-University Düsseldorf, Germany.
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MeSH Terms
Adaptation, Physiological
Brain / physiopathology*
Brain Infarction / complications,  physiopathology*
Brain Neoplasms / complications,  physiopathology*
Neuromuscular Diseases / etiology,  physiopathology*
Neuronal Plasticity*
Recovery of Function / physiology*

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