Document Detail


Reopening of internal carotid artery occlusions during heparin-induced LDL precipitation (H.E.L.P.) associated with improved haemorheology: report of 2 cases.
MedLine Citation:
PMID:  8333205     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
As has already been reported, there is a direct relationship between the severity of cerebrovascular insufficiency and elevated plasma fibrinogen levels, as well as whole blood and plasma viscosity, Red Cell Transit Time (RCTT) and cerebral blood flow. By applying heparin-induced extracorporeal LDL < cholesterol, triglycerides, fibrinogen > precipitation (H.E.L.P.), a rapid reduction of fibrinogen has become possible which has proved to be very beneficial for the treatment of acute stroke and multi-infarct disease. The present report demonstrates the impact of H.E.L.P. in connection with Doppler and Duplex sonography: In one patient a complete occlusion at the origin of the right internal carotid artery was revealed by Doppler and Duplex sonography. In a second patient, a complete occlusion of the left internal carotid artery was verified. By applying H.E.L.P. once a week (seven times in patient #1, twelve times in patient #2), a consistent lowering of fibrinogen, whole blood and plasma viscosity, red cell transit time, total cholesterol, low density lipoprotein, lipoprotein (a) and triglycerides was achieved. After H.E.L.P. application, Doppler/Duplex sonography showed complete reopening of the previously occluded vessel in patient #1 and patency of the vessel of patient #2.
Authors:
M Walzl; K Niederkorn; B Walzl; S Horner; H Lechner
Related Documents :
24051215 - Dragon's blood dropping pills have protective effects on focal cerebral ischemia rats m...
6249645 - The meaning of tissue po2 and local blood flow for the chemoreceptive process of the ca...
17614085 - Hypercapnia impact on vascular and neuronal reactivity in patients before and after car...
2406995 - Perfusion insufficiency in limb-shaking transient ischemic attacks.
22316645 - Barriers and enablers to introducing comprehensive patient blood management in the hosp...
9423975 - An evaluation of the system to control blood flow in maintaining goat fetuses on arteri...
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Wiener klinische Wochenschrift     Volume:  105     ISSN:  0043-5325     ISO Abbreviation:  Wien. Klin. Wochenschr.     Publication Date:  1993  
Date Detail:
Created Date:  1993-08-16     Completed Date:  1993-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  21620870R     Medline TA:  Wien Klin Wochenschr     Country:  AUSTRIA    
Other Details:
Languages:  eng     Pagination:  350-4     Citation Subset:  IM    
Affiliation:
Department of Neurology, Karl-Franzens University of Graz.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Brain Ischemia / blood,  therapy,  ultrasonography
Carotid Artery, Internal / ultrasonography
Carotid Stenosis / blood,  therapy*
Cholesterol, LDL / blood
Echoencephalography
Extracorporeal Circulation / instrumentation*
Fibrinogen / metabolism
Heparin / administration & dosage*
Humans
Lipoprotein(a) / blood
Lipoproteins, LDL / blood*
Male
Middle Aged
Triglycerides / blood
Chemical
Reg. No./Substance:
0/Cholesterol, LDL; 0/Lipoprotein(a); 0/Lipoproteins, LDL; 0/Triglycerides; 9001-32-5/Fibrinogen; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Antimicrobial susceptibility pattern of Neisseria gonorrhoeae in western Austria.
Next Document:  Postpartum factor VIII inhibitors. Report of two cases with special reference to the efficacy of var...