Document Detail

Renovascular hypertension: a noninvasive screening approach using captopril renography.
MedLine Citation:
PMID:  7572294     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Noninvasive cost-effective screening of hypertensive patients for renovascular hypertension is a desirable approach to a rare disorder. Currently many patients are screened with angiography, which is both invasive and expensive. METHODS: A MEDLINE search from 1985 through July 1994 using the key words "renovascular hypertension," "noninvasive," "screening" generated 16 references. We reviewed these references, as well as several additional references, in an effort to find a reliable noninvasive screening test for renovascular hypertension. RESULTS AND CONCLUSIONS: To date, the most reliable noninvasive screening test for renovascular hypertension is captopril renography. Results of captopril renography allow the physician to diagnose renovascular hypertension with an accuracy of greater than 90 percent. Cost-effectiveness requires appropriate selection of high-risk hypertensive patients for subsequent investigation with captopril renography. Hypertensive patients who have fibromuscular dysplasia, which is most commonly found in young white women, have the best treatment outcomes.
L S Bujenovic
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of the American Board of Family Practice / American Board of Family Practice     Volume:  8     ISSN:  0893-8652     ISO Abbreviation:  J Am Board Fam Pract     Publication Date:    1995 Jul-Aug
Date Detail:
Created Date:  1995-11-21     Completed Date:  1995-11-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8807505     Medline TA:  J Am Board Fam Pract     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  295-9     Citation Subset:  IM    
Department of Radiology, University of North Carolina Hospitals, Chapel Hill 27599, USA.
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MeSH Terms
Administration, Oral
Angiotensin-Converting Enzyme Inhibitors / administration & dosage,  diagnostic use
Antihypertensive Agents / administration & dosage,  diagnostic use
Captopril / administration & dosage,  diagnostic use*
Cost-Benefit Analysis
Hypertension, Renal / prevention & control*,  radionuclide imaging*
Mass Screening / economics,  methods
Patient Selection
Radioisotope Renography / economics,  methods*
Sensitivity and Specificity
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Antihypertensive Agents; 62571-86-2/Captopril

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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