| Renoprotective effect of mannitol infusion during extracorporeal shock lithotripsy. | |
| | |
MedLine Citation:
|
PMID: 19526157 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To evaluate the role of mannitol infusion in preventing or ameliorating renal injury that accompanies shock wave lithotripsy as measured by changes in resistive index (RI). METHODS: Between February and September 2006, 38 patients (28 men and 10 women) underwent extracorporeal shock wave lithotripsy (ESWL) for radiologically documented renal stones in The Surgical Specialties Hospital ESWL unit, Baghdad, Iraq. The 38 patients aged 20-50 years with renal stones of 10-20 mm size, scheduled for ESWL therapy, were divided into a control group (20 patients) and mannitol group (treatment group of 18 patients). All patients had their renal RI measured before ESWL, immediately after ESWL, then 3 and 7 days later. While patients in the mannitol group were given 0.5 gm/kg mannitol infusion during lithotripsy, the control group patients were given nothing. Changes in renal RI in both groups were evaluated statistically within the group and between the 2 groups. RESULTS: A significant rise in renal RI was found in the control group immediately after ESWL, then 3 and 7 days after. It increased from an initial value of 0.5875 to 0.6500, 0.6300, and 0.6245. The mannitol group showed fewer changes, yet still significant from 0.5850 to 0.6061, 0.6022, and 0.5967. This elevation of renal RI in the control group when compared to the mannitol group was statistically significant. CONCLUSION: Mannitol has a renoprotective function when given during ESWL, as evidenced by the statistically significant reduction in renal RI. |
| | |
Authors:
|
Samir A Muter; Usama N Rifat; Ziad H Abd |
Related Documents
:
|
18702247 - Cholecystectomy: indications at university of calabar teaching hospital, calabar, nigeria. 17144957 - Location modalities for focused extracorporeal shock wave application in the treatment ... 16689197 - Gelatin packing of intracortical tract after percutaneous nephrostomy lithotripsy for d... 15540747 - Comparison of 2 generations of piezoelectric lithotriptors using matched pair analysis. 7878417 - Sonic and ultrasonic scalers in a clinical comparison. a study in non-instructed patien... 19189117 - Kestenbaum procedure with posterior fixation suture for anomalous head posture in infan... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Saudi medical journal Volume: 30 ISSN: 0379-5284 ISO Abbreviation: Saudi Med J Publication Date: 2009 Jun |
Date Detail:
|
Created Date: 2009-06-15 Completed Date: 2009-08-31 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7909441 Medline TA: Saudi Med J Country: Saudi Arabia |
Other Details:
|
Languages: eng Pagination: 767-70 Citation Subset: IM |
Affiliation:
|
Department of Urology, Medical City Hospital, Baghdad, Iraq. dsamirali@yahoo.co.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Case-Control Studies Female Humans Kidney / drug effects* Lithotripsy / adverse effects* Male Mannitol / administration & dosage*, pharmacology Middle Aged |
| Chemical | |
Reg. No./Substance:
|
69-65-8/Mannitol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Berberine and total base from rhizoma coptis chinensis attenuate brain injury in an aluminum-induced...
Next Document: Hypotensive anesthesia with esmolol. Assessment of hemodynamics, consumption of anesthetic drugs, an...