| Renin-angiotensin system and stroke. | |
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MedLine Citation:
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PMID: 18690518 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The renin-angiotensin system (RAS) is a major regulatory system of cardiovascular and renal function. Many new aspects of this system have been revealed in recent years, leading to new therapeutic approaches. It's well known that RAS blocking agents have potent antiatherosclerotic effects, which are mediated by their antihypertensive, anti-inflammatory, antiproliferative, and oxidative stress lowering properties. Inhibitors of RAS are now first-line treatments for hypertensive target organ damage. Their effects are greater than expected by their ability to lower blood pressure. Angiotensin receptor blockers reduce the frequency of atrial fibrillation and stroke, are also able to prevent cardiovascular and renal events in diabetic patients. Thus, blockade of RAS represents one of the most important strategies in order to reduce cardiovascular risk. |
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Authors:
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Simona Marcheselli; Giuseppe Micieli |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology Volume: 29 Suppl 2 ISSN: 1590-1874 ISO Abbreviation: Neurol. Sci. Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-11 Completed Date: 2008-12-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100959175 Medline TA: Neurol Sci Country: Italy |
Other Details:
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Languages: eng Pagination: S277-8 Citation Subset: IM |
Affiliation:
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Neurologia I e Stroke Unit, IRCCS Istituto Clinico Humanitas, Rozzano, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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pharmacology,
therapeutic use Angiotensin-Converting Enzyme Inhibitors / pharmacology Angiotensins / antagonists & inhibitors*, metabolism Atrial Fibrillation / drug therapy, physiopathology, prevention & control Cerebrovascular Circulation / drug effects*, physiology Humans Receptors, Angiotensin / antagonists & inhibitors*, metabolism Renin-Angiotensin System / drug effects*, physiology* Stroke / metabolism, physiopathology*, prevention & control* Vasodilator Agents / pharmacology, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Angiotensins; 0/Receptors, Angiotensin; 0/Vasodilator Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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