| Renal vascular damage in systemic sclerosis patients without clinical evidence of nephropathy. | |
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MedLine Citation:
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PMID: 8651967 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the use of color-flow Doppler ultrasonography, a direct, noninvasive technique, for measurement of kidney blood flow in patients with systemic sclerosis (SSc). METHODS: Twenty-five normal volunteers and 25 SSc patients (median disease duration 8 years, range 2-21 years) were studied. All were free of clinical symptoms of renal damage. The resistance index (RI) was determined on main, interlobar, and cortical vessels. RESULTS: In SSc patients, the RI was significantly increased at every sampling site examined (P < 0.001). RI values were strongly correlated with disease duration (main artery r = 0.56, P < 0.04; interlobar artery r = 0.63, P < 0.02; cortical artery r = 0.75, P < 0.002). Regression analysis showed no relationship between RI and creatinine clearance values. CONCLUSION: Color-flow Doppler ultrasonography is a sensitive and noninvasive technique for evaluating vascular damage of the kidney in patients with SSc. |
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Authors:
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R Rivolta; B Mascagni; V Berruti; F Quarto Di Palo; A Elli; R Scorza; D Castagnone |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Arthritis and rheumatism Volume: 39 ISSN: 0004-3591 ISO Abbreviation: Arthritis Rheum. Publication Date: 1996 Jun |
Date Detail:
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Created Date: 1996-07-22 Completed Date: 1996-07-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370605 Medline TA: Arthritis Rheum Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1030-4 Citation Subset: AIM; IM |
Affiliation:
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Ospedale Maggiore di Milano, Milan, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Creatinine / blood, urine Female Humans Male Middle Aged Renal Circulation / physiology* Scleroderma, Systemic / physiopathology*, ultrasonography Sensitivity and Specificity Ultrasonography, Doppler, Color Vascular Resistance / physiology* |
| Chemical | |
Reg. No./Substance:
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60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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