Document Detail


Renal tubular dysgenesis in Israel: pathologist's experience and literature review.
MedLine Citation:
PMID:  19344005     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Renal tubular dysgenesis is a rare lethal kidney abnormality clinically manifested by olighydramnios, anuria and respiratory distress. Most of the information on this entity is provided by case reports and short series. OBJECTIVES: To evaluate the incidence and comparative frequency of clinical manifestations in different etiologic-pathogenic variants of RTD in Israel and in summarized published data. METHODS: Stillborn and neonatal autopsy material from nine medical centers in northern and central Israel was studied. Information concerning pregnancy, labor and postnatal status and autopsy findings of cases with histologically, histochemically and immunohistochemically confirmed RTD were obtained from corresponding reports and from published material. RESULTS: From the 1538 autopsies of fetuses (2 20 weeks gestation) and neonates that were performed between 1976 and 2007 we identified 12 cases of RTD (0.78%). Abnormality occurred more often (1.4%) in the Upper and Western Galilee than in Israel as a whole. CONCLUSIONS: Our study and a review of the literature showed that the autosomal recessive variant of RTD was more frequent than twin-twin transfusion-induced. Most symptoms were similar in all variants of RTD, but their frequency was different in each of them.
Authors:
Moisey Moldavsky
Related Documents :
22559395 - Reviews of acoustical patents.
1342875 - Three cases of oblique facial cleft: etiology, tomographic evaluation and reconstruction.
9239825 - Fetal hemoglobin changes in the twin oligohydramnios-polyhydramnios sequence.
2052505 - Cluster of iniencephaly in miami.
4290725 - Herpes simplex encephalitis: two fatal cases.
19911675 - An unusual presentation of blastomycosislike pyoderma (pyoderma vegetans) and a review ...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  The Israel Medical Association journal : IMAJ     Volume:  11     ISSN:  1565-1088     ISO Abbreviation:  Isr. Med. Assoc. J.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-04-06     Completed Date:  2009-05-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100930740     Medline TA:  Isr Med Assoc J     Country:  Israel    
Other Details:
Languages:  eng     Pagination:  6-10     Citation Subset:  IM    
Affiliation:
Department of Pathology, Ziv Medical Center, Safed, Israel. molmi@netvison.net.il
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Anuria / etiology*,  physiopathology
Autopsy
Congenital Abnormalities / diagnosis*,  epidemiology,  physiopathology*
Female
Humans
Incidence
Infant, Newborn
Israel / epidemiology
Kidney Tubules / abnormalities*
Male
Oligohydramnios / etiology*,  physiopathology
Pregnancy
Respiratory Distress Syndrome, Newborn / etiology*,  physiopathology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Benchmarking for maximum value.
Next Document:  Decreased TFF2 expression in the gastric antrum in patients infected with CagA-positive Helicobacter...