Document Detail


Renal sympathetic denervation: hypertension therapy and beyond.
MedLine Citation:
PMID:  23668705     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Hypertension is one of the most important treatable causes of mortality and morbidity in the world, but despite the wide availability of pharamacological therapy, blood pressure is poorly controlled in many patients. Renal sympathetic denervation (RSD) is a novel therapeutic option whereby the renal sympathetic nerves, which lie within and around the wall of the renal arteries, are ablated using a catheter placed within the arterial lumen. The Symplicity HTN-2 trial has shown that RSD reduces blood pressure to a clinically relevant degree; this finding has resulted in an explosion in interest in the procedure and RSD has the potential to become a standard therapy for many hypertensive patients. Many new devices are in development that will simplify the procedure, and several novel indications for RSD are currently being investigated in clinical trials.
Authors:
Paul D Williams; Rob Whitbourn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Expert review of medical devices     Volume:  10     ISSN:  1745-2422     ISO Abbreviation:  Expert Rev Med Devices     Publication Date:  2013 May 
Date Detail:
Created Date:  2013-05-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230445     Medline TA:  Expert Rev Med Devices     Country:  England    
Other Details:
Languages:  eng     Pagination:  329-38     Citation Subset:  IM    
Affiliation:
St Vincent's Hospital, 41 Victoria Parade, Fitzroy, Melbourne, VIC 3065, Australia.
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