| Renal salt wasting as part of dysautonomia in Guillain-Barre syndrome. | |
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MedLine Citation:
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PMID: 20732865 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cerebral salt-wasting syndrome and the syndrome of inappropriate antidiuresis (SIAD) are the most important causes of non-iatrogenic hyponatraemia that can significantly complicate various brain diseases. Salt wasting without an underlying CNS disease may have been disregarded so far by clinicians and has been described as renal salt-wasting (RSW) in patients as drug side effect (eg, cisplatin), in older people with various common diseases (eg, hip fracture, pulmonary infections) and other sporadic conditions. In Guillain-Barré Syndrome (GBS), however, hyponatraemia has been described mainly as SIAD. However, symptoms of hyponatraemia rarely develop in GBS. Here, we report on a woman with GBS with dominant symptoms of dysautonomia and moderate severe hyponatraemia. We could identify RSW as part of the autonomic dysfunction that significantly contributed to disease worsening. |
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Authors:
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T Lenhard; C Grimm; P A Ringleb |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-08-22 |
Journal Detail:
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Title: Journal of neurology, neurosurgery, and psychiatry Volume: 82 ISSN: 1468-330X ISO Abbreviation: J. Neurol. Neurosurg. Psychiatr. Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-08-08 Completed Date: 2011-09-30 Revised Date: 2012-03-16 |
Medline Journal Info:
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Nlm Unique ID: 2985191R Medline TA: J Neurol Neurosurg Psychiatry Country: England |
Other Details:
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Languages: eng Pagination: 1051-3 Citation Subset: IM |
Affiliation:
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Department of Neurology, University Hospital of Heidelberg, Heidelberg, Germany. thorsten.lenhard@med.uni-heidelberg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Albumins / metabolism Constipation / etiology Demyelinating Diseases / pathology Electrophysiological Phenomena Female Gait Disorders, Neurologic / etiology Guillain-Barre Syndrome / complications*, diagnosis, metabolism* Humans Hyponatremia / etiology*, metabolism* Kidney / metabolism* Primary Dysautonomias / etiology*, metabolism* Sodium / blood, urine Urinary Bladder / ultrasonography Urination Disorders / etiology |
| Chemical | |
Reg. No./Substance:
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0/Albumins; 7440-23-5/Sodium |
| Comments/Corrections | |
Comment In:
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J Neurol Neurosurg Psychiatry. 2012 Mar;83(3):344-5
[PMID:
21335571
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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