| Renal perfusion: pharmacologic changes depicted with power Doppler US in an animal model. | |
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MedLine Citation:
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PMID: 7480728 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the ability of power Doppler ultrasonography to depict changes in renal perfusion after pharmacologic manipulations. MATERIALS AND METHODS: Six domestic swine were intubated and anesthetized. The right renal artery was catheterized for injection of epinephrine (100 micrograms) and papaverine (2 mg/kg). Intraarterial blood pressure, heart rate, and oxygen saturation were measured continuously. Longitudinal images of the kidney were obtained, and the power Doppler color map was analyzed subjectively and by computer at baseline and at the time of maximum drug effect. RESULTS: Epinephrine produced vasoconstriction with a diminished power Doppler color map and a decrease in both subjective and computer scores. After papaverine-induced vasodilatation, the power Doppler map was enhanced, as reflected by increased subjective and computer scores. CONCLUSION: The power Doppler color map reflects anticipated changes in renal perfusion after alterations in blood flow by vasoactive drugs. |
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Authors:
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J E Durick; T C Winter; U P Schmiedl; D R Cyr; F L Starr; L A Mack |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 197 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1995 Dec |
Date Detail:
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Created Date: 1995-12-21 Completed Date: 1995-12-21 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 615-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University of Washington, Seattle, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / drug effects Disease Models, Animal Epinephrine / administration & dosage, pharmacology Female Heart Rate / drug effects Image Enhancement / methods Image Processing, Computer-Assisted Injections, Intra-Arterial Kidney / ultrasonography* Male Oxygen / blood Papaverine / administration & dosage, pharmacology Renal Artery Renal Circulation / drug effects* Swine Ultrasonography, Doppler, Color / methods* Vasoconstrictor Agents / administration & dosage, pharmacology Vasodilator Agents / administration & dosage, pharmacology Video Recording |
| Chemical | |
Reg. No./Substance:
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0/Vasoconstrictor Agents; 0/Vasodilator Agents; 51-43-4/Epinephrine; 58-74-2/Papaverine; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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