Document Detail


Renal nerves and sodium conservation in conscious rats of different strains kept on various diets.
MedLine Citation:
PMID:  3249662     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Earlier contradictory results as to whether renal nerves are necessary for adaptation to a low dietary sodium intake in the rat were ascribed to strain differences or to sympathetic stimulation caused by carbohydrates when changing from a low-sucrose normal-sodium diet to a high-sucrose sodium-deficient diet. In the present work, daily sodium excretion was studied for 4 days before and after bilateral renal denervation or sham operation in three strains of rats (CFY, Wistar, and Long Evans). After ingesting a normal sodium diet containing no sucrose, CFY and Wistar rats were fed a sodium-deficient diet containing 67% sucrose. Long Evans rats were sodium-depleted by feeding them boiled rice. Daily and cumulative sodium excretion and sodium balance were similar in all three groups during 4-day sodium-depletion periods before and after bilateral renal denervation or sham operation. The results suggest that in sodium-depleted rats denervation natriuresis can be ascribed neither to strain differences nor to the high sucrose content of the low-sodium diet.
Authors:
L Takács; G Szénási; P Bencsáth
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta medica Hungarica     Volume:  45     ISSN:  0236-5286     ISO Abbreviation:  Acta Med Hung     Publication Date:  1988  
Date Detail:
Created Date:  1989-07-10     Completed Date:  1989-07-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8400269     Medline TA:  Acta Med Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  365-75     Citation Subset:  IM    
Affiliation:
Division of Clinical Immunology, Nephrology and Endocrinology, Joint Research Organization of the Hungarian Academy of Sciences, Budapest.
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MeSH Terms
Descriptor/Qualifier:
Animals
Body Weight
Diet*
Diet, Sodium-Restricted
Kidney / innervation*,  physiology
Male
Potassium / urine
Rats
Rats, Inbred Strains
Reference Values
Sodium / metabolism*,  urine
Species Specificity
Sympathectomy
Chemical
Reg. No./Substance:
7440-09-7/Potassium; 7440-23-5/Sodium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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