| Renal microradiography of experimental ureteral obstruction in the rabbit. | |
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MedLine Citation:
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PMID: 2585647 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Microradiography of nephrons in kidneys perfusion-fixed with glutaraldehyde permits examination of large numbers of nephrons. This technique was applied to rabbits between one and 14 days following unilateral ureteral ligation. Kidneys without ureteral occlusion served as controls. By two days after ureteral obstruction there was dilatation of the ducts of Bellini and papillary collecting ducts. At three to four days there was splaying and tortuosity of the loops of Henle. By eight to 10 days the proximal straight tubules were noted to be dilated and helically twisted. After two weeks of ureteral obstruction there was dilatation of Bowman's space with encroachment on the glomerular capillary tuft. At this time many proximal convoluted tubules began to show atrophic changes. These morphologic alterations may due in part to back pressure on the nephrons, with retrograde progression as the duration of urinary tract obstruction is increased. The distal convoluted tubule and the descending limb of the loop of Henle were not noted to be abnormal during the study. |
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Authors:
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R Gade; D A Feinfeld; M F Gade |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Journal of urology Volume: 142 ISSN: 0022-5347 ISO Abbreviation: J. Urol. Publication Date: 1989 Dec |
Date Detail:
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Created Date: 1989-12-28 Completed Date: 1989-12-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0376374 Medline TA: J Urol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1619-23 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, St. Barnabas Hospital, Bronx, New York. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Dilatation, Pathologic / etiology, pathology, radiography Female Ligation / methods Microradiography* / methods Nephrons / pathology, radiography* Rabbits Time Factors Ureteral Obstruction / etiology, pathology, radiography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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