| Renal hilus paraganglioma: a case report and brief review. | |
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MedLine Citation:
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PMID: 19886555 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Paraganglioma is a rare tumour that originates from any paraganglia. Among extra-adrenal paraganglioma, renal hilus is a rare location. The authors report a case of a 43-year-old female who was admitted for evaluation of a renal mass detected incidentally by ultrasound imaging. Suspecting malignancy, the patient underwent radical nephrectomy. Upon macroscopic examination, the lesion was located into the renal hilus. Histological study revealed a neoplasm constituted of nests of monomorphic cuboidal cells with basophilic granular cytoplasm and round to oval nuclei. Necrosis was absent. The proliferative index (Mib-1) was very low (< 5%). Immunohistochemical examination revealed reactivity for neuron specific enolase (NSE), chromogranin A and synaptophysin. The final diagnosis was renal hilus paraganglioma. The paper shows the difficulty in diagnostic approaches to paraganglioma in this atypical site. |
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Authors:
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F Pagni; E Galbiati; F Bono; C Di Bella |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pathologica Volume: 101 ISSN: 0031-2983 ISO Abbreviation: Pathologica Publication Date: 2009 Apr |
Date Detail:
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Created Date: 2009-11-05 Completed Date: 2009-12-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401123 Medline TA: Pathologica Country: Italy |
Other Details:
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Languages: eng Pagination: 89-92 Citation Subset: IM |
Affiliation:
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University Milan Bicocca, Desio Hospital, Italy. petala.83@tiscali.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Carcinoma, Renal Cell / pathology Carcinoma, Transitional Cell / pathology Diagnosis, Differential Female Humans Immunohistochemistry Kidney Neoplasms / metabolism, pathology*, surgery Nephrectomy Paraganglioma, Extra-Adrenal / metabolism, pathology*, surgery Pelvic Neoplasms / pathology |
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