| Renal function parameters during early and late recovery periods following an all-out 21-km run in trained adolescent runners. | |
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MedLine Citation:
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PMID: 21466418 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Background: This study investigated the changes in biomarkers of renal function and the corresponding estimated glomerular filtration rate (eGFR) in 10 male adolescent (16.2±0.6 years) trained runners during early and late recovery periods after an all-out 21-km run. Methods: Venous blood samples were taken immediately before, and at 2-h, 4-h, and 24-h following the 21-km run. Samples were analyzed for hemoglobin (Hb) and hematocrit (Hct), and serum urea (U), creatinine (Cr), creatine kinase (CK) and lactate dehydrogenase (LDH). U/Cr ratio, eGFR, and plasma volume change (%ΔPV) were calculated based on the associated measured variables. Results: At 2-h and 4-h, there were increases (26%-146%) in U, Cr, U/Cr, CK, and LDH, and decreases (8%-13%) in Hb and Hct, as compared with the corresponding pre-exercise values. The calculated %ΔPV increased by 17% while the eGFR decreased 20% from the corresponding pre-exercise value, respectively. At 24-h, the changes of the blood variables and renal function parameters observed at early recovery period were sustained. Conclusions: Taken together, the findings of this study suggest that mild decline in renal function occurred during the early recovery period following the 21-km run. The decline in renal function did not return to normal during the later recovery period. |
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Authors:
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Ye Tian; Tom K Tong; Giuseppe Lippi; Chuanye Huang; Qingde Shi; Jinlei Nie |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-6 |
Journal Detail:
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Title: Clinical chemistry and laboratory medicine : CCLM / FESCC Volume: - ISSN: 1434-6621 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-6 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9806306 Medline TA: Clin Chem Lab Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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China Institute of Sport Science, Beijing, P.R. China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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