Document Detail


Renal failure and cardiovascular risk
MedLine Citation:
PMID:  16633986     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Prevalent studies concerning chronic renal failure (CRF) in the general adult population, using the Crockroft-Gault formula correcting serum creatinine values for calibration factors, indicate that about 22.8% have initial CRF. If the albuminuria itself is considered as an index of renal damage, we find a prevalence rate in the adult population of about 8.5%, with slight differences between females and males. Considering only this second more optimistic statistic and comparing it with the number of patients on dialysis, evidenced by the different specific registers, we observe that only 2% of the population with renal failure reach terminal uremia; and therefore, require substitutive therapy or renal transplantation. For many years, statistical analyzes have been carried out on the prevalence of pathologies present in patients who arrive at dialysis; to date, little has been done for patients with initial or average renal failure. Few of these studies are prospective. The data of studies concerning the elderly population suffering from CFR of varying degrees, as well as the data of longitudinal studies concerning patients controlled for a few years, have shown that cardiovascular diseases (CVD) are more responsible for the mortality of patients with even modest renal failure before reaching uremia compared to patients without renal failure. On the contrary, statistics on the prevalence of CVD in patients who arrive at dialysis are well-known, it can be >70%. Different organizations such as the National Kidney Foundation, the American Heart Association and the Seventh Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure have considered the presence of CRF a cardiovascular risk factor.
Authors:
L Iorio
Publication Detail:
Type:  English Abstract; Journal Article; Review    
Journal Detail:
Title:  Giornale italiano di nefrologia : organo ufficiale della Società italiana di nefrologia     Volume:  23 Suppl 34     ISSN:  0393-5590     ISO Abbreviation:  G Ital Nefrol     Publication Date:    2006 Jan-Feb
Date Detail:
Created Date:  2006-04-24     Completed Date:  2006-07-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9426434     Medline TA:  G Ital Nefrol     Country:  Italy    
Other Details:
Languages:  ita     Pagination:  S3-6     Citation Subset:  IM    
Affiliation:
U.O. Nefrologia e Dialisi, Ospedale Gemma De Bosis, Cassino (FR). uonefro.cassino@libero.it
Vernacular Title:
Carta del rischio vascolare renale.
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MeSH Terms
Descriptor/Qualifier:
Cardiovascular Diseases / etiology*
Humans
Kidney Failure, Chronic / complications*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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