| Renal cell carcinoma: real-time contrast-enhanced ultrasound findings. | |
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MedLine Citation:
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PMID: 19844755 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the findings of renal cell carcinomas (RCCs) on contrast-enhanced ultrasound (CEUS). METHODS: CEUS features of 84 RCCs confirmed by pathologic examination in 81 patients were retrospectively analyzed. A contrast-specific mode and a sulfur hexafluoride-filled microbubble contrast agent were used for CEUS. The enhancement pattern, extent, and dynamic change in the cortical, corticomedullary, and late phases were evaluated. RESULTS: On CEUS, the emergence of tumor enhancement was earlier in two nodules (2.4%), simultaneous in 71 (84.5%), and later in 11 (13.1%), in comparison with the adjacent renal cortex. Seventy-four RCC nodules (88.1%) showed hyper-enhancement (n = 2) or iso-enhancement (n = 72) during the cortical phase, and the remaining 10 (11.9%) showed hypo-enhancement. Twenty-three nodules (27.4%) showed homogeneous enhancement and 61 (72.6%) inhomogeneous enhancement. In the corticomedullary phase, the nodules showed hypo-enhancement in 68 (81.0%) and iso-enhancement in 16 (19.0%). In the late phase, all RCCs showed the same enhancement pattern as that shown in the corticomedullary phase. Seventy-two (85.7%) nodules showed a clear perilesional rim-like enhancement in late phase. CONCLUSIONS: Hyper- or iso-enhancement during the cortical phase, subsequent washout in late phase, inhomogeneous enhancement, and perilesional rim-like enhancement are clues for RCCs, which might be useful for characterization of RCCs. |
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Authors:
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Zuo-Feng Xu; Hui-Xiong Xu; Xiao-Yan Xie; Guang-Jian Liu; Yan-Ling Zheng; Jin-Yu Liang; Ming-De Lu |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Abdominal imaging Volume: 35 ISSN: 1432-0509 ISO Abbreviation: Abdom Imaging Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 750-6 Citation Subset: IM |
Affiliation:
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Department of Medical Ultrasonics, The First Affiliated Hospital, Institute of Diagnostic and Interventional Ultrasound, Sun Yat-Sen University, Guangzhou, China. |
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Comment In:
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Abdom Imaging. 2010 Aug;35(4):507-9
[PMID:
20148247
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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